Results 61 to 70 of about 1,766,452 (265)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Evaluation of Radiation Rates and Health Hazards from Different Cement Types in Pakistan

open access: yesAtmosphere
The raw materials of cement contain radioactive elements that come from natural sources. Members of the decay chains of uranium, thorium, and potassium radioisotope 40K are the primary sources of this radioactivity. The natural radionuclide concentration
Muhammad Waseem   +7 more
doaj   +1 more source

Estimation of radiation dose rates' changes on Hb using dielectric parameters

open access: yesArab Journal of Basic and Applied Sciences, 2019
In this paper we will introduce several physical parameters that are very promising to use as indicators to diagnose and prognose tissue, cellular and molecular status.
Mohamed M. M. Elnasharty, Azhar M. Elwan
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Space Environment Monitoring Unit on Wentian Laboratory Cabin Module of China Space Station

open access: yesAerospace
This article introduces the design and development of a space environment monitoring unit embedded in the versatile experimental assembly for electronic components outside the China space station’s Wentian laboratory cabin module.
Huanxin Zhang   +7 more
doaj   +1 more source

CALCULATION OF THE IRRADIATION DOSE FOR SOME COMPONENTS OF THE FOOD CHAIN OF THE FRESHWATER ECOSYSTEM OF THE YENISEI RIVER, DURING THE OPERATION OF THE NUCLEAR FUEL CYCLE ENTERPRISE – THE MINING AND CHEMICAL COMBINE, KRASNOYARSK

open access: yesРадиационная гигиена, 2018
This study is focused on the evaluation of the levels of accumulation of the man-made radionuclides by several components of Yenisei River close to the water discharge spot of the Mining and chemical plant containing a significant amount of man-made ...
V. N. Rakitsky   +2 more
doaj   +1 more source

Dose Rate Definition in Brachytherapy

open access: yesTurkish Journal of Oncology, 2019
Brachytherapy (BRT) is defined as treatment from a short distance. The word is derived from the word "brachy" that means "short" in Greek. Treatment in BRT is performed by placing the radioactive source in or near the tumor tissue. According to the report 38 of the International Commission on Radiation Units and Measurements (ICRU ...
openaire   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Identification of the contributors (Ag-110 m) for higher radiation field on primary heat transport system of Tarapur Atomic Power Station-3 and its impact on collective dose

open access: yesRadiation Protection and Environment, 2018
Tarapur Atomic Power Station-3 is 540 MWe pressurized heavy water reactor in India, it achieved first criticality on May 5, 2006 and then operated at full power.
Villas Mahadev Sonwalkar   +4 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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