Results 1 to 10 of about 1,370,829 (119)

Dose reduction of biologics in patients with plaque psoriasis: a review

Frontiers in Pharmacology
Dose reduction (DR) of first-generation biologics for plaque psoriasis (TNF-alpha inhibitors (i) and interleukin (IL)-12/23i) has been described in a previous scoping review.
C. A. M. van Riel, C. A. M. van Riel, C. A. J. Michielsens, C. A. J. Michielsens, M. E. van Muijen, M. E. van Muijen, L. S. van der Schoot, L. S. van der Schoot, J. M. P. A. van den Reek, J. M. P. A. van den Reek, E. M. G. J. de Jong, E. M. G. J. de Jong, E. M. G. J. de Jong   +12 more
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Serum drug levels and anti-drug antibodies in the context of dose tapering by interval prolongation of adalimumab, etanercept and ustekinumab in psoriasis patients: results of the CONDOR trial

Journal of Dermatological Treatment, 2022
Background Biologics for psoriasis are registered in standard dosages. In patients with low disease activity, reduction of the dose by interval prolongation can prevent overtreatment, and lower risks and costs.
Selma Atalay, Sophie E. Berends, Hans M. M. Groenewoud, Ron A. A. Mathot, David M. Njoo, Johannes M. Mommers, Paul M. Ossenkoppele, Marjolein I. A. Koetsier, Maartje A. Berends, Annick de Vries, Peter C. M. van de Kerkhof, Alfons A. den Broeder, Elke M. G. J. de Jong, Juul M. P. A. van den Reek   +13 more
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Generative Adversarial Network (Generative Artificial Intelligence) in Pediatric Radiology: A Systematic Review

Children, 2023
Generative artificial intelligence, especially with regard to the generative adversarial network (GAN), is an important research area in radiology as evidenced by a number of literature reviews on the role of GAN in radiology published in the last few ...
Curtise K. C. Ng
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Impact of Tracer Dose Reduction in [18 F]-Labelled Fluorodeoxyglucose-Positron Emission Tomography ([18 F]-FDG)-PET) on Texture Features and Histogram Indices: A Study in Homogeneous Tissues of Phantom and Patient

Tomography, 2023
Background: Histogram indices (HIs) and texture features (TFs) are considered to play an important role in future oncologic PET-imaging and it is unknown how these indices are affected by changes of tracer doses.
Jonas Vogel, Ferdinand Seith, Arne Estler, Konstantin Nikolaou, Holger Schmidt, Christian la Fougère, Thomas Küstner   +6 more
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Ultra-Low-Dose Whole-Body Computed Tomography Protocol Optimization for Patients With Plasma Cell Disorders: Diagnostic Accuracy and Effective Dose Analysis From a Reference Center

Frontiers in Oncology, 2021
BackgroundThe whole-body low-dose CT (WBLDCT) is the first-choice imaging technique in patients with suspected plasma cell disorder to assess the presence of osteolytic lesions.
Davide Tore, Osvaldo Rampado, Carla Guarnaccia, Roberto Mina, Maria Oronzio, Ambra Santonocito, Alessandro Serafini, Giulio Antonino Strazzarino, Laura Gianusso, Sara Bringhen, Paolo Fonio, Alessandro Depaoli   +11 more
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Dose Finding and Food Effect Studies of a Novel Abiraterone Acetate Formulation for Oral Suspension in Comparison to a Reference Formulation in Healthy Male Subjects

Pharmaceutics, 2021
Currently approved formulations of the androgen synthesis inhibitor abiraterone acetate (AA) consist of multiple tablets administered daily in a fasted state.
Tamás Jordán, Orsolya Basa-Dénes, Réka Angi, János Orosz, Zsolt Ötvös, Andrea Ujhelyi, Genovéva Filipcsei, László Molnár, Tamás Solymosi, Hristos Glavinas, Dominic Capone, Nicola Whitfield, John McDermott, Litza McKenzie, Lauren Shurety, Elizabeth Manning Duus   +15 more
doaj   +1 more source

Clinical outcomes of dose modification during pirfenidone treatment for IPF: A nationwide post-marketing surveillance study

Frontiers in Pharmacology, 2023
Background: Pirfenidone, an antifibrotic medication approved for the treatment of idiopathic pulmonary fibrosis (IPF), often requires dose reduction owing to adverse events.
Jieun Kang, Man Pyo Chung, Moo Suk Park, In Jae Oh, Heung Bum Lee, Young Whan Kim, Jong Sun Park, Soo Taek Uh, Yun Seong Kim, Yangjin Jegal, Jin Woo Song   +10 more
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Reduction in Radiation Exposure of CT Perfusion by Optimized Imaging Timing Using Temporal Information of the Preceding CT Angiography of the Carotid Artery in the Stroke Protocol

Diagnostics, 2022
(1) Background: CT perfusion (CTP) is a fast, robust and widely available but dose-exposing imaging technique for infarct core and penumbra detection. Carotid CT angiography (CTA) can precede CTP in the stroke protocol.
Zsuzsanna Deak, Lara Schuettoff, Ann-Kathrin Lohse, Matthias Fabritius, Paul Reidler, Robert Forbrig, Wolfgang Kunz, Konstantin Dimitriadis, Jens Ricke, Bastian Sabel   +9 more
doaj   +1 more source

Do radiographers collimate? A retrospective analysis of radiographic collimation of common musculoskeletal examinations at an adult trauma centre

Journal of Medical Radiation Sciences, 2023
Introduction Collimation of the primary beam is an important factor in radiography to reduce dose and improve image quality. The introduction of larger detector plates in direct digital radiography (DR) allows the exposed area to be calculated by ...
Sally Ball, Megan McKerrow, Andrew Murphy   +2 more
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The comparison between fixed versus degressive doses of medroxyprogesterone acetate combined with letrozole in patients of progestin-primed ovarian stimulation protocol: a propensity score-matched study

Frontiers in Endocrinology, 2023
ObjectiveTo explore the cycle characteristics and pregnancy outcomes of progestin-primed ovarian stimulation (PPOS) using fixed versus degressive doses of medroxyprogesterone acetate (MPA) in conjunction with letrozole (LE) in infertile women by ...
Ying Zhang, Ying Zhang, Ying Zhang, Ying Zhang, Ying Zhang, Hao Li, Hao Li, Shanshan Zhu, Shanshan Zhu, Shanshan Zhu, Shanshan Zhu, Shanshan Zhu, Shengfang Jiang, Shengfang Jiang, Shengfang Jiang, Shengfang Jiang, Shengfang Jiang, Wenxian Zhao, Wenxian Zhao, Xiaoning Wang, Xiaoning Wang, Xiaoning Wang, Xiaoning Wang, Xiaoning Wang, Liu Tian, Liu Tian, Liu Tian, Liu Tian, Liu Tian, Guangming Zhao, Guangming Zhao, Guangming Zhao, Nongqiao He, Nongqiao He, Nongqiao He, Honglu Diao, Honglu Diao, Honglu Diao, Honglu Diao, Honglu Diao, Hong Cao, Changjun Zhang, Changjun Zhang, Changjun Zhang, Changjun Zhang, Changjun Zhang   +45 more
doaj   +1 more source