Results 141 to 150 of about 116,309 (297)

The use of thermoluminescent dosimeters for In-vivo dosimetry in a fast neutron therapy beam [PDF]

, 2000
Bibliography: leaves 72-77.Thermoluminescent detectors (TLD-700) have been investigated for absorbed dose measurements in a p(66)/Be neutron therapy beam at the National Accelerator Centre.
Bhengu, Khumbulani John
core   +1 more source

Safety, efficacy, pharmacokinetics, and mechanisms of novel 10B‐boronophenylalanine combined with a radio‐frequency quadrupole accelerator in boron neutron capture therapy: A preclinical study in head and neck squamous cell carcinoma

Precision Radiation Oncology, EarlyView.
This study demonstrates that the novel 10B‐BPA‐based BNCT system, combined with an RFQ accelerator, effectively targets head and neck squamous cell carcinoma. It induces tumor regression safely and efficiently by triggering DNA damage and activating the ROS/HIF‐1α/NF‐κB pathway, leading to caspase‐3‐mediated apoptosis.
Zhaoyuan Zhang, Junyan Li, Minhua Fan, Huafu Ouyang, Qiubo Chu, Huijie Yan, Yannan Zheng, Linxuan Huang, Gui Bao, Zhenting Ma, Shaobo Huang, Lin Li, Xiao Xu, Zhigang Liu   +13 more
wiley   +1 more source

Normal tissue complication probability models of late cardiopulmonary toxicity following deep inspiration breath hold for breast cancer adjuvant radiotherapy

Precision Radiation Oncology, EarlyView.
Deep inspiration breath hold (DIBH) markedly cuts heart and left lung radiation doses during left‐sided breast cancer radiotherapy. The normal tissue complication probability (NTCP) model further confirms lower predicted cardiopulmonary toxicities versus free breathing (FB), potentially improving patients’ quality of life.
Lin Lin, Liang Liu, Zhengxin Gao, Yaling Hong, Qing Gong, Zhan Yu, Xue Liu, Qiaoying Hu, Yongqiang Li, Shen Fu, Qi Yu   +10 more
wiley   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: from immune mechanisms to clinical practice

Precision Radiation Oncology, EarlyView.
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen, Minxiao Yi, Yu Deng, Qian Shen   +3 more
wiley   +1 more source

MR‐Linac Successfully Guided the Treatment of a Free‐Moving Mesenteric Mass

Precision Radiation Oncology, EarlyView.
This case demonstrated that a mesenteric tumor could move significantly day‐to‐day in all directions with large volume change. MR‐Linac with online adaptive capability provided a superior platform to treat mobile target with significantly reduced normal tissue exposure to radiation .
Xin Wang, Tze Yee Lim, He Wang, Bouthaina Shbib Dabaja, Jinzhong Yang   +4 more
wiley   +1 more source

Toxicity of High-Density Polyethylene Nanoparticles in Combination with Silver Nanoparticles to Caco-2 and HT29MTX Cells Growing in 2D or 3D Culture

Molecules
The enormous applications of various nanoparticles (NPs) have raised the possibility that humans may be simultaneously exposed to mixtures of them in real life.
Sylwia Męczyńska-Wielgosz, Katarzyna Sikorska, Malwina Czerwińska, Agnieszka Grzelak, Anna Lankoff, Marcin Kruszewski   +5 more
doaj   +1 more source

C–X–C Motif Chemokine Receptor 4 (CXCR4)‐Targeted Biologically Guided Proton Spatially Fractionated Radiotherapy for Bulky Limited‐Stage Small Cell Lung Cancer

Precision Radiation Oncology, EarlyView.
A newly proposed proton spatially fractionated radiotherapy guided by biological imaging Abstract Background and Purpose To evaluate the feasibility and dosimetric safety of integrating C–X–C motif chemokine receptor 4 (CXCR4)‐targeted tracer 18F‐AlF‐NOTA‐QHY‐04 positron emission tomography imaging with biologically guided proton spatially fractionated
Keru Pu, Tengxiang Li, Shengnan Xu, Xue Sha, Qingtao Qiu, Jinming Yu, Yong Yin, Jie Liu   +7 more
wiley   +1 more source

Optimal irradiation parameters for the development of the sterile insect technique in the seedcorn maggot Delia platura (Diptera: Anthomyiidae)

Pest Management Science, EarlyView.
X‐ray irradiation of Delia platura pupae showed that 20 Gy induces high sterility while maintaining male quality and competitiveness, establishing optimal parameters for sterile insect technique implementation in North America. Abstract BACKGROUND The seedcorn maggot, Delia platura Meigen (Diptera: Anthomyiidae), is a sporadic but economically ...
Anne‐Marie Fortier, Allen Bush‐Beaupré, Jade Savage, Jacques Brodeur   +3 more
wiley   +1 more source

No evidence of the long-term in vitro toxicity of Aeroxide P25 TiO2 nanoparticles in three mammalian cell lines despite the initial reduction of cellular mitochondrial activity

Nukleonika
We studied the effects of Aeroxide P25 titanium dioxide nanoparticles (TiO2 NPs) with a diameter of 21 nm on induction of DNA damage and long-term survival of three human cell lines: hepatocellular liver carcinoma HepG2, colorectal adenocarcinoma HT29 ...
Męczyńska-Wielgosz Sylwia, Bartłomiejczyk Teresa, Grądzka Iwona, Sommer Sylwester, Węgierek-Ciuk Aneta, Lankoff Anna, Sikorska Katarzyna, Wojewódzka Maria, Dobrzyńska Małgorzata, Kruszewski Marcin   +9 more
doaj   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source