Results 31 to 40 of about 91,110 (269)

El vacío del corazón

open access: yesAULA Revista de Humanidades y Ciencias Sociales
Para llegar al cielo, como diría Julio Cortázar, tan solo se requiere una piedrita y la punta de un zapato; y tal es quizá lo necesario para adentrarse en la espesura de la rayuela que es el pensamiento de María Zambrano. Apenas se ha pensado acerca del
Borja López Arranz
doaj   +3 more sources

Through the lens of marketing authorization holders: experience in use of real‐world data and real‐world evidence in drug development and regulatory submissions in EU

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this study was to assess the general and product‐specific experiences of MAHs use of RWD/RWE in medicines development and in their regulatory submissions, and to explore organizational aspects of MAHs related to RWD/RWE. Methods An electronic survey was conducted, and information collected directly from MAHs.
Sini M. Eskola   +5 more
wiley   +1 more source

Historia de la industria en México, siglos XIX y XX

open access: yesH-Industri@
Presentacion del dossier sobre historia de la industria en Mexico durante los siglo XIX y XX.
Juan Odisio   +1 more
doaj   +1 more source

Form flows function: Learner‐centered game Re‐design in a STEM classroom

open access: yesBritish Educational Research Journal, EarlyView.
Abstract Re‐designing games facilitates interest‐driven learning and immerses learners in systems thinking. However, there are limited studies exploring how the form and function of tabletop games influence learners' design decisions and learning experiences. To address this gap, we conducted a mixed‐methods study in a STEM classroom in western Canada.
Farzan Baradaran Rahimi   +2 more
wiley   +1 more source

The transversality of ICTs applied in the pedagogical strategy Integrative training dossier

open access: yesRevista Ingenio, 2015
Higher education institutions must train students to become well-informed and deeply motivated citizens, equipped with a critical sense and capable of analyzing society's problems, seeking solutions for those that arise in society, applying these and ...
Marta Milena Peñaranda Peñaranda
doaj   +1 more source

Mimic, target, and adapt: Cell membrane‐coated nanoplatforms for precision and immune‐guided cancer treatment

open access: yesBMEMat, EarlyView.
This Perspective explores the emerging landscape of cell membrane‐coated nanoparticles (CM‐NPs) as intelligent, immune‐compatible platforms for cancer therapy. Highlighting design strategies, translational challenges, and competitive positioning, it outlines how integrating biomimetic targeting with advanced analytical and manufacturing tools could ...
A. K. M. M. Alam   +4 more
wiley   +1 more source

Schülerexperimente zur Synthese naturidentischer, geruchsaktiver Ester im Mikromaßstab durch alkalisch katalysierte Umesterung von Glyceriden

open access: yesCHEMKON, EarlyView.
In diesem Beitrag wird ein einfaches Schülerexperiment vorgestellt, bei dem durch Umesterung von Triacylglyceriden mit n‐Alkanolen im Mikromaßstab geruchsaktive Alkylalkanoate hergestellt werden. Die Reaktion erfolgt alkalisch katalysiert bei Raumtemperatur in kleinen Gefäßen; es entstehen flüchtige Ester mit charakteristischen Frucht‐ und ...
Horst Klemeyer
wiley   +1 more source

La industria siderúrgica en la Argentina, segunda mitad del siglo XX

open access: yesH-Industri@, 2008
En este número de H-industri@ presentamos un dossier sobre la evolución de la industria siderúrgica de la Argentina en el crucial período comprendido entre 1947 y 1990; es decir, desde la aparición del sector en la “agenda” de las preocupaciones ...
Martín Schorr
doaj   +2 more sources

Safety evaluation of the food enzyme glucan 1,4-α-glucosidase from the non-genetically modified <i>Aspergillus niger</i> strain AE-GN. [PDF]

open access: yesEFSA J
Abstract The food enzyme glucan 1,4‐α‐glucosidase (4‐α‐d‐glucan α‐glucohydrolase; EC 3.2.1.3) is produced with the non‐genetically modified Aspergillus niger strain AE‐GN by Amano Enzyme Inc. The food enzyme was considered free from viable cells of the production organism. It is intended to be used in 13 food manufacturing processes.
EFSA Panel on Food Enzymes (FEZ)   +20 more
europepmc   +2 more sources

Safety evaluation of the food enzyme β-glucosidase from the genetically modified <i>Trichoderma reesei</i> strain DP-Nyk114. [PDF]

open access: yesEFSA J
Abstract The food enzyme β‐glucosidase (β‐d‐glucoside glucohydrolase; EC 3.2.1.21) is produced with the genetically modified Trichoderma reesei strain DP‐Nyk114 by Genencor International B.V. The genetic modifications do not give rise to safety concerns. The food enzyme was considered free from viable cells of the production organism and its DNA. It is
EFSA Panel on Food Enzymes (FEZ)   +17 more
europepmc   +2 more sources

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