Results 161 to 170 of about 1,459,434 (319)
Comparative Test of the Effectiveness of Netilmicin and Sisomicinon Respiratory Tract Infection by Double Blind Method
, 1983 Atsushi Saitô, Jingoro Shimada, Masahisa OOMORI, Kooya SHIBA, Takehisa Yamaji, Hironobu Ihara, Toshio Hōjō, Masanobu Kaji, Mikio SAEGUSA, Tadashi Miyahara, Yasushi Ueda, Kazuo Takebe, Kenichi Imamura, Yoshihiro KUMASAKA, Yuzuru Fujioka, Aiichiro Kurihara, Hisashi Nakahata, Hiroyuki Kobayashi, Mituko TAKAMURA, Michiro NAKASHIMA, Keishi Hashimoto, Takashi Taniguchi, Takehiko Sakurami, Kazumi NOZU, Fumio Nagahama, Shinya YASUDA, Takehito NAKABAYASHI, Tetsushi Koroku, Takahisa Saito, Hiroshi Kon, N Konno, Akira Nakazato, Yomei HIRAGA, Koki KIKUCHI, K Suzuki, A Kuse, Osamu Mitsuhashi, Wakamatsu Tokio, Rensuke KURODA, Nobuichi OHSHIMA, Michiyasu HONDA, Yoshiro Ishii, Kiyoshi KONDO, Masayoshi Nishida, Yuichiro FUKASAWA, Sanpachi SAKUMA, C Itoh, Keisuke Takeuchi, Kazuhiko Tanabe, Hiromitsu KONDO, Hagime INOOKA, Y Haneda, Norimasa Narita, Naoyoshi MASAKI, Toyokazu Tamura, K Aoyagi, Yasuhisa Abe, Mikihiko Kudou, S Kosaka, Ken‐ichi Kimura, Koumei YOSHIOKA, Yoshihiro TUTUI, Katsuhiro OKAMOTO, Tadanao OMI, Shuichiro Yoshida, Hiroyasu Kawabe, Masatoku OTA, Masao Tamura, Takashi Itoh, Mikio Matsui, Nobuhisa SATO, Izumi Hayashi, Setsuo KOBAYASHI, R Fueki, HIDEO OZEKI, Tôru Nagasawa, Motoichi Tanaka, Kaoru Shimada, Takashi Inamatsu, T Takigami, Toshio Fukui, Hiroshi Nakamura, Kaoru OHYAMA, Naoki Suzuki, Hiromi Kato, Hidehiko Suzuki, Masakatsu SUGIMORI, Naohiro Yamashita, Saburo Yano, Nobuo Ohya, Mitsuru Hayase, Hirofumi Kato, Kikuo Sugimoto, Chiyoo SUMIYA, Toshio Okuno, Kazuhiko KOSUGA, Yasuo Hosomi, Yoshio Takahashi, Hidekazu Hata, Sinobu Kinehara +99 moreopenalex +2 more sourcesNeuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT
Advanced Science, EarlyView.Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye +8 morewiley +1 more sourceSemaphorin 3E–Plexin D1 Axis Drives Lung Fibrosis through ErbB2‐Mediated Fibroblast Activation
Advanced Science, EarlyView.TGF‐β1 stimulation in fibroblasts leads to increased Furin expression, Furin‐mediated cleavage of P87‐Sema3E to P61‐Sema3E, which affects fibroblast function through the autocrine pathway, and the P61‐Sema3E‐PlexinD1 axis promotes fibroblast activation, proliferation and migration by affecting ErbB2 phosphorylation, which in turn activates the ErbB2 ...Zhesong Deng, Jinkun Chen, Ruonan Yang, Yuan Zhan, Shanshan Chen, Jiaheng Zhang, Hao Fu, Yiya Gu, Qian Huang, Jixing Wu, Lianyu Shan, Abdelilah Soussi Gounni, Jungang Xie +12 morewiley +1 more sourceMitigating Doxorubicin‐Induced Cardiotoxicity and Enhancing Anti‐Tumor Efficacy with a Metformin‐Integrated Self‐Assembled Nanomedicine
Advanced Science, EarlyView.A novel self‐assembled nanomedicine (PMDDH) has been developed for the co‐delivery of doxorubicin and metformin, aiming to enhance the anti‐tumor efficacy of doxorubicin while alleviating its cardiotoxicity through the activation of cGAS‐STING and AMPK signaling pathways, respectively.Jiaxin Huang, Jieru Yang, Yuanying Yang, Xiaofeng Lu, Juan Xu, Shan Lu, Hong Pan, Wenhu Zhou, Wenqun Li, Songwen Chen +9 morewiley +1 more sourceM6A Modified miR‐31‐5p Suppresses M1 Macrophage Polarization and Autoimmune Dry Eye by Targeting P2RX7
Advanced Science, EarlyView.The upregulation of FTO in autoimmune dry eye suppresses the recognition of pri‐miR‐31 by DGCR8, thereby inhibiting the maturation of miR‐31‐5p and reducing its inhibitory effect on the target gene P2RX7. The activation of P2RX7 subsequently triggers the p38 MAPK signaling pathway and increases the level of M1‐related genes, thus exacerbating the ...Lu Zhao, Xuejia Li, Min Gao, Lin Liu, Binyun Ma, Xun Liu, Jiachen Zhang, Ruoxuan Liu, Bei Du, Ruihua Wei, Hong Nian +10 morewiley +1 more sourceIncrease in Colonic PRopionate as a Method of prEVENTing Weight Gain Over 12 Months in Adults Aged 20–40 Years ((iPREVENT): A Multi-Centre, Double-Blind, Randomised, Parallel-Group Trial [PDF]
Jennifer E Pugh, Katerina Petropoulou, Joana C. Vasconcelos, Aisha Anjum, George Thom, Louise McCombie, Martina Tashkova, Sumayya Alshehhi, Daphne Babalis, Leah Holroyd, Barzan A. Sadiq, Christina Prechtl, Tom Preston, Michael EJ Lean, Waljit S. Dhillo, A Toby Prevost, Douglas J. Morrison, Gary Frost +17 moreopenalex +2 more sourcesThe Effect of Intraoperative Systemic Lidocaine on Postoperative Persistent Pain Using Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials Criteria Assessment Following Breast Cancer Surgery: A Randomized, Double‐Blind, Placebo‐Controlled Trial
, 2017 Mark C. Kendall, Robert J. McCarthy, Steve Panaro, Emily Goodwin, Jane M. Bialek, Antoun Nader, Gildàsio S. De Oliveira +6 moreopenalex +1 more source