Results 191 to 200 of about 1,671,076 (389)
MicroRNA‐375‐3p Targets Fatty Acid Synthase and Relish to Regulate Energy Allocation During Pupal Metamorphosis and Starvation
Advanced Science, EarlyView.During pupal metamorphosis and starvation, elevated 20‐hydroxyecdysone (20E) and suppressed insulin trigger Forkhead box O (FOXO) nuclear translocation, enhancing miR‐375‐3p expression. This downregulates fatty acid synthase (FASN) and Relish, promoting lipid breakdown for energy while prioritizing antioxidant responses over immune functions to support Peng Chen, Meiqi Cheng, Jianhui Wang, Jing Tang, Xiaoqiao Huang, Yusi Li, Huiling Zhou, Ling Zhang, Yi Dong, Chengjun Li, Bin Li +10 morewiley +1 more sourceSupplementary Methods S1 from Randomized, Double-Blind, Placebo-Controlled Trial of MUC1 Peptide Vaccine for Prevention of Recurrent Colorectal Adenoma
, 2023 Robert E. Schoen, Lisa A. Boardman, Marcia Cruz‐Correa, Ajay Bansal, David Kastenberg, Chin Hur, Lynda Dzubinski, Sharon F. Kaufman, Luz M. Rodriguez, Ellen Richmond, Asad Umar, Éva Szabó, Andres Μ. Salazar, John McKolanis, Pamela Beatty, Reetesh K. Pai, Aatur D. Singhi, Camille M. Jacqueline, Riyue Bao, Brenda Diergaarde, Ryan P. McMurray, Carrie Strand, Nathan R. Foster, David M. Zahrieh, Paul J. Limburg, Olivera J. Finn +25 moreopenalex +1 more sourceAnti‐Apoptotic and Neurite‐Protective Nanomedicine Augments Embryonic Stem Cells‐Derived Retinal Ganglion Cell Transplantation in Glaucoma Recovery
Advanced Science, EarlyView.Lithium‐epigallocatechin gallate nanoparticles (Li‐EGCG NPs) are co‐transplanted with embryonic stem cell‐derived retinal ganglion cells (ESC‐RGCs) to enhance cell survival and therapeutic efficacy in an acute pathological glaucomatous injury model. This synergistic approach protects RGC cells, preserves retinal structure and improves visual function ...Moxin Chen, Xiaoyan Jiang, Yuanhui Wang, Zhaobin Luo, Yu Zhang, Siwei Liu, Rui Huang, Dandan Zhang, Zhimin Tang, Yahan Ju, Shaohui Pan, Ni Ni, Wei Feng, Yu Chen, Ping Gu +14 morewiley +1 more sourceSGLT2 inhibitors versus GLP-1 receptor agonists for major adverse cardiovascular events in type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. [PDF]
BMC Cardiovasc DisordAhmed AAO, Ahmed OAO, Ahmed RAO, Ahmed RAO, Mohammed MAEA, Ahmed Y, Abbas M, Ibrahim MAA, Abakar MEM, Dahab KEM, Elbashir RMA, Mohamed KH, Mansour MA. +12 moreeuropepmc +1 more sourceITGB1 Regulates Triple‐Negative Breast Cancer Development by Modulating the Tumor Microenvironment
Advanced Science, EarlyView.ABSTRACT
Tumorigenesis and metastasis are frequently attributed to the intricate interplay between cancer cells and the tumor microenvironment (TME). Comprehending the mechanisms and key regulators of cancer‐immune crosstalk in the TME is imperative for developing efficacious immunotherapy.Nuozi Song, Siqi Chen, Lei Wang, Jessica Dang, Xu Cao, Stephanie Singh, Lu Yang, Jinhui Wang, Steven T. Rosen, Yingyu Wang, Chun‐Wei D. Chen, Cheng Zhang, Mingye Feng +12 morewiley +1 more sourceEffect of Transcranial Direct Current Stimulation Combined With Rehabilitation on Arm and Hand Function in Stroke Patients: A Systematic Review and Meta-Analysis. [PDF]
CureusOdeh BA, Alotaibi F, Khamis BH, Almugren NF, Aljazi AS, Lasloom MS, Alshahrani RD, Almutairi EM, Zafarani MA, Alshammari KF, Alsamiri S, Jabr YS, Alhirsan SM. +12 moreeuropepmc +1 more sourceComparison of Clinical Efficacy of Rokitamycin (RKM) and Ofloxacin (OFLX) for the Treatment of Campylobacter Enteritis by a Double-Blind Method
, 1991 Mitsuo Obana, Isao TOMIZAWA, Yoshihiko TAKIZAWA, Y. Nitta, Hiroko SAGARA, Takehisa SEO, Junichi Sato, Takafumi TSUNODA, Satomi OTA, A. Machii, Yoshitaka Nakamura, Teiko KATANO, Misako MURATA, Kenji Ohnishi, Tsuyoshi Yamaguchi, Gohta MASUDA, Masayoshi Negishi, Atsushi Ajisawa, Mitsuo Kitahara, Keiko LEE, Shoichiro Irimajiri, Yasuo Matsuoka, Fumio MATSUMOTO, Takeo Imai, Iwao Sakurai, Takayuki Takahashi, Fukiko AMANO, Akira MURAMOTO, Chié Nakamura, Hideyuki KANOU, Jun Naruse, Yong-Ki Kim, Yasuhiko Inamoto, Mitsuru AKAO, Yoshihiro Sakaue, Shiro Hosoda, Tadao Bamba, Kenichi Tatewaki, Kunio Yoshikawa, I Matsushita, K Fuse, Masaya Sasaki, K Kurisu, Masao Nakagawa, Katsuyuki Kitoh, Toshio KAWAJIRI, Minoru Kizu, Takehiko Shiomi, Sadao KATAOKA, Yoshio Kawaguchi, Akira Fukumoto, Kazuya Tamura, Masami Murai, Michio Tanaka, Osamu Kurimura, Yoshio MATSUBARA, Makoto Saito, Yatsuka IMAGAWA, Rintaro NAKAYA, Sankichi Horiuchi, Yoshio Inagaki +60 moreopenalex +2 more sourcesTEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration
Advanced Science, EarlyView.TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang +9 morewiley +1 more sourceAnalgesic strategies for ischaemic pain in chronic limb-threatening ischaemia: a systematic review and meta-analysis. [PDF]
Pain RepDavies H, Boalot A, Howitt A, Vleugels MJ, Tam SKP, Kwan JY, Black S, Francis I, Bull C, Mees BME, Mitchell S, Russell D. +11 moreeuropepmc +1 more sourceEfficacy and safety of recombinant human soluble thrombomodulin (ART‐123) in disseminated intravascular coagulation: results of a phase III, randomized, double‐blind clinical trial
Journal of Thrombosis and Haemostasis, 2007 H. Saito, I. Maruyama, S. Shimazaki, Yasuhiro Yamamoto, N. Aikawa, R. Ohno, A. Hirayama, T. Matsuda, H. Asakura, M. Nakashima, N. Aoki +10 moresemanticscholar +1 more source
