Results 221 to 230 of about 1,630,882 (368)

SAT-105 ALLOPURINOL FOR CVD IN CKD (AVOID-CKD): A DOUBLE BLIND, RANDOMIZED CONTROLLED TRIAL: DESIGN AND METHODS

open access: gold, 2020
Vijay P. Kumar   +5 more
openalex   +1 more source

Rational Design and Organoid‐Based Evaluation of a Cocktail CAR‐γδ T Cell Therapy for Heterogeneous Glioblastoma

open access: yesAdvanced Science, EarlyView.
A novel “prof” cocktail therapy is designed. It screens antigens, selects personalized antigen panels, engineers optimized CAR‐Vδ1 T cells, and tests in patient‐derived GBM organoids, offering hope for effective CAR‐T drugs against heterogeneous solid tumors. Abstract Various challenges, including tumor heterogeneity and inadequate T cell infiltration,
Guidong Zhu   +12 more
wiley   +1 more source

Effect of a Single Preventive Intravenous Dose of Ketorolac and Paracetamol on Reducing Postoperative Pain in Septorhinoplasty Patients: Double-Blind Randomized Clinical Trial. [PDF]

open access: yesIran J Med Sci
Dehghanpisheh L   +9 more
europepmc   +1 more source

Clinical evaluation of gingival massage agent (LPD) on gingivitis and marginal periodontitis by double-blind method.

open access: bronze, 1984
Satoshi YAMASHITA   +11 more
openalex   +2 more sources

Enhanced Broadband Acoustic Absorption in Commercial Foam via Multiwall Carbon Nanotube‐Induced Pore Reconstruction

open access: yesAdvanced Science, EarlyView.
A simple to multiscale structure transition happens when a commercial porous foam is filled with multiwall carbon nanotubes with high aspect ratio. For an acoustic absorber with a porous material, the loading of multiwall carbon nanotubes can significantly improve its specific surface area while preserving its thickness and high porosity, thus enables ...
Jinkui Xiong   +11 more
wiley   +1 more source

Cardiac Slc25a49‐Mediated Energy Reprogramming Governs Doxorubicin‐Induced Cardiomyopathy through the G6P–AP‐1–Sln Axis

open access: yesAdvanced Science, EarlyView.
Doxorubicin‐induced cardiomyopathy involves mitochondrial energy metabolism dysfunction, exacerbated by cardiomyocyte‐specific Slc25a49 deficiency via oxidative phosphorylation (OXPHOS) suppression and glycolysis activation. The Slc25a49–glucose‐6‐phosphate (G6P)–activator protein‐1 (AP‐1) axis drives myocardial injury by upregulating Sln, disrupting ...
Sitong Wan   +16 more
wiley   +1 more source

Cardioprotective Glucose-Lowering Agents and Dementia Risk: A Systematic Review and Meta-Analysis.

open access: yesJAMA Neurol
Seminer A   +7 more
europepmc   +1 more source

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

open access: yesAdvanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang   +16 more
wiley   +1 more source

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