Results 231 to 240 of about 701,417 (304)

Integrative Analyses Identify a cGAS‐STING Pathway‐Driven Signature With Context‐Dependent Roles in Systemic Lupus Erythematosus

Advanced Science, EarlyView.
Zhang et al. identify M7core, a critical cGAS‐STING pathway‐driven gene signature that is activated in most lupus patients’ blood and links to lupus disease severity, lymphopenia, and lupus nephritis. They further reveal the diagnostic and pathogenic characteristics of M7core and emphasize the importance of assessing pathway activity before initiating ...
Lele Zhang, Ming‐Ju Amy Lyu, Ze Hong, Jing Sun, Lan Guo, Jiameng Hu, Munire Maimaiti, Chenhui Li, Jinyi Song, Xiang Zhang, Huansha Yu, Chen Wang, Xuan Wang, Haiyang Hu   +13 more
wiley   +1 more source

Loss of VMP1 Impairs Tight Junction Recycling and Aggravates Intestinal Barrier Dysfunction in Inflammatory Bowel Disease

Advanced Science, EarlyView.
This study identifies vacuole membrane protein 1 (VMP1) as a critical regulator of intestinal epithelial barrier homeostasis. VMP1 facilitates the recruitment of CORO1C to late endosomes, supporting Retromer‐mediated recycling of the tight junction protein Occludin.
Jiawei Zhao, Jianjun Zou, Chen Zhou, Yingui Wang, Yiman Liu, Yanqing Zhou, Yuxiang Wang, Xinyu Zhang, Huishu Yang, Hongjie Yin, Dongsheng Bai, Yue Zhao, Na Lu   +12 more
wiley   +1 more source

Integrated iPRISM Direct-on-Urine Platform for Rapid UTI Diagnosis in a Double-Blind Clinical Trial. [PDF]

ACS Meas Sci Au
Jiang X, Fishler R, Ron G, Boguslavsky K, Halachmi S, Segal E.   +5 more
europepmc   +1 more source

The effects of cocoa products in individuals with metabolic syndrome and related diseases: a systematic review and meta-analysis. [PDF]

J Diabetes Metab Disord
Gomes Chagas A, Camilotti BG, Gonçalves GN, de Macedo LR, Silva M.   +4 more
europepmc   +1 more source

Moringa oleifera Lamk. as a Promising Adjunct Therapeutic Candidate: A Narrative Review of Human Studies and Published Case Reports. [PDF]

Drug Des Devel Ther
Sianipar EA, Sumiwi SA, Susilawati Y, Levita J.   +3 more
europepmc   +1 more source

Efficacy of botulinum toxin type A for spasticity management and motor function in children with cerebral palsy: a systematic review and meta-analysis of randomized controlled trials. [PDF]

Front Neurol
Alghadier M, Alsuwayegh A.
europepmc   +1 more source

Resveratrol and Renal Biomarkers in Type 2 Diabetes: An Updated Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Diabetes Metab Syndr Obes
Gu W, Mu N, Yan Y, Shi L, Yang F.
europepmc   +1 more source