Results 41 to 50 of about 702,312 (347)

Pharmacological Treatment of Postprandial Reductions in Blood Pressure : A Systematic Review [PDF]

, 2015
Funded by The Dunhill Medical Trust.
Alam, Aronow, Freeman, Gentilcore, Heseltine, Heseltine, Hirayama, Jansen, Jansen, Jansen, Jansen, Jian, Jones, Jones, Lenders, Lipsitz, Lipsitz, Moher, O'Donovan, Onrot, Potter, Rakic, Russo, Sawynok, Shibao, Vaitkevicius, Visvanathan, Vloet, Vloet   +28 more
core   +1 more source

NEW WAYS OF PEER REVIEWING IN JOURNALS: OPEN REVIEW

Pensar en Movimiento, 2015
Technology has helped improve many aspects of the quality of publications: more visibility, greater access to sources of information and option to verify those sources, among others.
Andrea Mora-Campos
doaj   +1 more source

Secukinumab versus adalimumab for psoriatic arthritis: comparative effectiveness up to 48 weeks using a matching-adjusted indirect comparison [PDF]

, 2018
Secukinumab and adalimumab are approved for adults with active psoriatic arthritis (PsA). In the absence of direct randomized controlled trial (RCT) data, matching-adjusted indirect comparison can estimate the comparative effectiveness in anti-tumor ...
Gandhi, Kunal, Hunger, Matthias, Jugl, Steffen M., Karabis, Andreas, McInnes, Iain B., Mease, Philip J., Mpofu, Shephard, Nash, Peter, Thom, Howard   +8 more
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Gabapentin for tinnitus: a systematic review.

, 2011
PURPOSE: The main aim of this study was to assess the effect of gabapentin on tinnitus via a systematic review. METHOD: An electronic search of literature as well as a hand search were conducted. Only double-blind randomized controlled trials (RCTs) that
Amr El Refaie, Andersson G., Bakhshaee M., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Brunnberg E., Budd R. J., Daftary A., Delb W., Dias A., Gabapentin for tinnitus, Goldstein B. A., Green S., Hashir Aazh, Henry J. A., Higgins J. P. T., Hiller W., Kozoroski Kanashiro A. M., Luxon L., McNair D. M., Milbrandt J. C., Moffat G., Moore B. C., Mrena R., Nelson J. J., Nicolas-Puel C., Nondahl D. M., Noreña A. J., Noreña A. J., Ochi K., Parra L. C., Piccirillo J. F., Rachel Humphriss, Ratnayake S. A., Russell D., Salviati M., Sataloff R. T., Schlee W., Schulz K. F., Shulman A., Shulman A., Shulman A., Surr R. K., Taylor C. P., Temmel A. F., Watanabe M., Witsell D. L., Zapp J. J.   +51 more
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Developing Placebos for Clinical Research in Traditional Chinese Medicine: Assessing Organoleptic Properties of Three Dosage Forms (Oral Liquid, Capsule and Granule)

Frontiers in Pharmacology, 2021
Background: The successful application of randomized, double-blind placebo-controlled studies requires maximum blinding. Organoleptic properties of the placebo should be similar to the drug, making it difficult to distinguish between the two.
Mengli Xiao, Mengli Xiao, Jiake Ying, Jiake Ying, Yang Zhao, Yang Zhao, Qingna Li, Qingna Li, Yingpan Zhao, Rui Gao, Rui Gao, Fang Lu, Fang Lu   +12 more
doaj   +1 more source

Antiviral treatment for Bell's palsy (idiopathic facial paralysis) [PDF]

, 2009
BACKGROUND: Antiviral agents against herpes simplex virus are widely used in the treatment of idiopathic facial paralysis (Bell's palsy), but their effectiveness is uncertain. Significant morbidity can be associated with severe cases.
Abiko, Adour, Adour KK Swanson, Ahangar, Allen, Allen, Antunes, Aquino, Axelsson, Bateman, Brandenberg, Chen, Diego, Egger, Engström, Goudakos, Hato, Hato, Hernández, House, Hultcranzt, Ibarrondo, Inanli, Katusic, Kawaguchi, May, McCormick, Morgan, Morgenlander, Murakami, Petruzelli, Pietersen, Pietersen, Ramos Macias, Ross, Rowlands, Roy, Salinas, Sipe, Stjernquist-Desatnik, Sugita, Sullivan, Takasu, Theil, Wolf, Yanagihara, Yeo, Zhou   +47 more
core   +3 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source