Results 51 to 60 of about 1,671,076 (389)

Developing Placebos for Clinical Research in Traditional Chinese Medicine: Assessing Organoleptic Properties of Three Dosage Forms (Oral Liquid, Capsule and Granule)

Frontiers in Pharmacology, 2021
Background: The successful application of randomized, double-blind placebo-controlled studies requires maximum blinding. Organoleptic properties of the placebo should be similar to the drug, making it difficult to distinguish between the two.
Mengli Xiao, Mengli Xiao, Jiake Ying, Jiake Ying, Yang Zhao, Yang Zhao, Qingna Li, Qingna Li, Yingpan Zhao, Rui Gao, Rui Gao, Fang Lu, Fang Lu   +12 more
doaj   +1 more source

PROTIZINIC ACID FOR ACUTE CYSTITIS : EVALUATION BY A DOUBLE BLIND METHOD [PDF]

, 1976
Effect of protizinic acid as an adjuvant to antibiotics was evaluated in acute simple cystitis by a double blind method using bendinamine hydrochloride as a control drug.
平岡, 真, 日景, 高志
core  

Gabapentin for tinnitus: a systematic review.

, 2011
PURPOSE: The main aim of this study was to assess the effect of gabapentin on tinnitus via a systematic review. METHOD: An electronic search of literature as well as a hand search were conducted. Only double-blind randomized controlled trials (RCTs) that
Amr El Refaie, Andersson G., Bakhshaee M., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Bauer C. A., Brunnberg E., Budd R. J., Daftary A., Delb W., Dias A., Gabapentin for tinnitus, Goldstein B. A., Green S., Hashir Aazh, Henry J. A., Higgins J. P. T., Hiller W., Kozoroski Kanashiro A. M., Luxon L., McNair D. M., Milbrandt J. C., Moffat G., Moore B. C., Mrena R., Nelson J. J., Nicolas-Puel C., Nondahl D. M., Noreña A. J., Noreña A. J., Ochi K., Parra L. C., Piccirillo J. F., Rachel Humphriss, Ratnayake S. A., Russell D., Salviati M., Sataloff R. T., Schlee W., Schulz K. F., Shulman A., Shulman A., Shulman A., Surr R. K., Taylor C. P., Temmel A. F., Watanabe M., Witsell D. L., Zapp J. J.   +51 more
core   +1 more source

Pharmacological Treatment of Postprandial Reductions in Blood Pressure : A Systematic Review [PDF]

, 2015
Funded by The Dunhill Medical Trust.
Alam, Aronow, Freeman, Gentilcore, Heseltine, Heseltine, Hirayama, Jansen, Jansen, Jansen, Jansen, Jian, Jones, Jones, Lenders, Lipsitz, Lipsitz, Moher, O'Donovan, Onrot, Potter, Rakic, Russo, Sawynok, Shibao, Vaitkevicius, Visvanathan, Vloet, Vloet   +28 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

The PATCH trial: efficacy and safety of 5% lidocaine-medicated plaster for the treatment of patients with trigeminal neuralgia: a study protocol for a multicentric, double-blind, enriched enrolment randomised withdrawal, vehicle-controlled study

BMJ Open, 2021
Introduction Trigeminal neuralgia (TN) is characterised by a sudden, severe, electric shock like paroxysmal pain, which is almost always associated with triggers. Carbamazepine is the first-line medical management of TN. However, side effects are common.
Fang Luo, Chunmei Zhao, Ying Shen, Hongbing Liu, Niti Shrestha, Lan Meng, Bifa Fan   +6 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

SEMI-BLIND SOURCE SEPARATION FOR ESTIMATION OF CLAY CONTENT OVER SEMI-VEGETATED AREAS, FROM VNIR/SWIR HYPERSPECTRAL AIRBORNE DATA [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The applicability of Visible, Near-Infrared and Short Wave Infrared (VNIR/SWIR) hyperspectral imagery for soil property mapping decreases when surfaces are partially covered by vegetation.
W. Ouerghemmi, C. Gomez, S. Nacer, P. Lagacherie   +3 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Intra-articular injections with corticosteroids and sodium hyaluronate for treating temporomandibular joint disorders: a systematic review

Dental Press Journal of Orthodontics, 2013
INTRODUCTION: In some cases, conservative treatment of internal derangements of the Temporomandibular Joint (TMJ) is considered little responsive. Thus, it is necessary to accomplish treatments that aim at reducing pain and improve patients' functions ...
Eduardo Machado, Daniel Bonotto, Paulo Afonso Cunali   +2 more
doaj   +1 more source