Results 51 to 60 of about 702,312 (347)

The PATCH trial: efficacy and safety of 5% lidocaine-medicated plaster for the treatment of patients with trigeminal neuralgia: a study protocol for a multicentric, double-blind, enriched enrolment randomised withdrawal, vehicle-controlled study

BMJ Open, 2021
Introduction Trigeminal neuralgia (TN) is characterised by a sudden, severe, electric shock like paroxysmal pain, which is almost always associated with triggers. Carbamazepine is the first-line medical management of TN. However, side effects are common.
Fang Luo, Chunmei Zhao, Ying Shen, Hongbing Liu, Niti Shrestha, Lan Meng, Bifa Fan   +6 more
doaj   +1 more source

PROTIZINIC ACID FOR ACUTE CYSTITIS : EVALUATION BY A DOUBLE BLIND METHOD [PDF]

, 1976
Effect of protizinic acid as an adjuvant to antibiotics was evaluated in acute simple cystitis by a double blind method using bendinamine hydrochloride as a control drug.
平岡, 真, 日景, 高志
core  

Steroids in pediatric eosinophilic esophagitis [PDF]

, 2014
Swallowed fluticasone and oral viscous budesonide are effective first-line therapies for eosinophilic esophagitis in children. Side effects are minimal without evidence of Cushing syndrome, as seen in treatment with systemic corticosteroids.
Contreras, Emily M., Gupta, Sandeep K.
core   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

SEMI-BLIND SOURCE SEPARATION FOR ESTIMATION OF CLAY CONTENT OVER SEMI-VEGETATED AREAS, FROM VNIR/SWIR HYPERSPECTRAL AIRBORNE DATA [PDF]

The International Archives of the Photogrammetry, Remote Sensing and Spatial Information Sciences, 2015
The applicability of Visible, Near-Infrared and Short Wave Infrared (VNIR/SWIR) hyperspectral imagery for soil property mapping decreases when surfaces are partially covered by vegetation.
W. Ouerghemmi, C. Gomez, S. Nacer, P. Lagacherie   +3 more
doaj   +1 more source

Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials. [PDF]

, 2007
BACKGROUND: Treatment efficacy of physical agents in osteoarthritis of the knee (OAK) pain has been largely unknown, and this systematic review was aimed at assessing their short-term efficacies for pain relief.
A Andrianakos, A Fargas-Babjak, A Gur, A Khadilkar, A Molsberger, A White, AF Shaughnessy, Anne E Ljunggren, AR Jadad, AS Quirk, B Hegedus, B Lewis, B Nivbrant, BM Berman, Bård Bogen, C Sangdee, C Witt, CJ Derry, CR Smith, D Carroll, D Lewis, DH Trock, DH Trock, DJ Hunter, DT Felson, E Naredo, EM Roos, ES Pessoa, EW Ehrich, F Angst, F Song, F Tubach, GL Cheing, H Jensen, HH Dubben, J Low, J Stelian, J Vas, Jan M Bjordal, JB Walker, JH Kellgren, JM Bjordal, JM Bjordal, JM Bjordal, JM Bjordal, JM Bjordal, JM Bjordal, JP Ioannidis, K Grimmer, K Ishimaru, KA Sluka, KD Brandt, KG Baker, KM Jordan, KM Jordan, L Brosseau, L Chesterton, M Egger, M Osiri, M Yurtkuran, M Yurtkuran, Mark I Johnson, MI Johnson, MJ Smith, MJA Klaber, MP Steultjens, N Bellamy, N Bellamy, N Pipitone, N Wiebe, P Barlas, P Nicolakis, P Taylor, P White, PM Bulow, PM Peloso, PP Law, R Defrin, R Lubart, Roberta Chow, Rodrigo AB Lopes-Martins, S Götte, SM Cowan, T Harlow, VJ Robertson, W Takeda, World Association for Laser Therapy - WALT   +86 more
core   +5 more sources

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini, Paolo Preziosa, Paola Valsasina, Damiano Mistri, Monica Margoni, Federica Esposito, Massimo Filippi, Maria A. Rocca   +7 more
wiley   +1 more source

Intra-articular injections with corticosteroids and sodium hyaluronate for treating temporomandibular joint disorders: a systematic review

Dental Press Journal of Orthodontics, 2013
INTRODUCTION: In some cases, conservative treatment of internal derangements of the Temporomandibular Joint (TMJ) is considered little responsive. Thus, it is necessary to accomplish treatments that aim at reducing pain and improve patients' functions ...
Eduardo Machado, Daniel Bonotto, Paulo Afonso Cunali   +2 more
doaj   +1 more source

The Effect of Nopalea™, a Nutritional Supplement Containing Cactus Fruit Juice, on C-Reactive Protein Levels in Healthy Adults Assessed using a Randomized, Double-Blind, and Controlled Experimental Design [PDF]

, 2014
This study was developed to investigate the anti-inflammatory effects of a commercial product (Nopalea™) containing Prickly Pear Cactus Fruit Juice in 286 healthy adults.
Diefenbach, Patricia, Mattie, Mark, Patel, Sarwat, Schmeck, Cynthia, Tsnobiladze, Medeya   +4 more
core  

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source