Secukinumab versus adalimumab for psoriatic arthritis: comparative effectiveness up to 48 weeks using a matching-adjusted indirect comparison [PDF]
Secukinumab and adalimumab are approved for adults with active psoriatic arthritis (PsA). In the absence of direct randomized controlled trial (RCT) data, matching-adjusted indirect comparison can estimate the comparative effectiveness in anti-tumor ...
Gandhi, Kunal+8 more
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X-ray image separation via coupled dictionary learning [PDF]
In support of art investigation, we propose a new source sepa- ration method that unmixes a single X-ray scan acquired from double-sided paintings. Unlike prior source separation meth- ods, which are based on statistical or structural incoherence of the ...
Cornelis, Bruno+4 more
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Treatments for spasticity and pain in multiple sclerosis: a systematic review [PDF]
Objectives: To identify the drug treatments currently available for the management of spasticity and pain in multiple sclerosis (MS), and to evaluate their clinical and cost-effectiveness.
Beard, S.M., Hunn, A., Wight, J.
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The development of wireless communication technologies will lead to an increase of rapid-time-variants featured occasions and physical occasions of small-data-size communication in network, and the modulation system diversification resulting from social ...
Xin Liu+3 more
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Effect of meprobamate on the vestibulosensory and vestibular somatic reaction [PDF]
The influence of meprobamate on the vestibular illusion of counter-rotation, movement coordination and vertical writing was investigated by a double blind trial method and placebo.
Khinchikashvili, N. V.
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Challenges recruiting to a proof-of-concept pharmaceutical trial for a rare disease: The trigeminal neuralgia experience [PDF]
Background: This study aimed to describe recruitment challenges encountered during a phase IIa study of vixotrigine, a state and use-dependent Nav1.7 channel blocker, in individuals with trigeminal neuralgia.
Bendtsen, Lars+10 more
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COPD associated pulmonary hypertension: A post hoc analysis of the PERFECT study
The PERFECT study, a randomized, controlled, double‐blind study of inhaled treprostinil in patients with COPD and associated pulmonary hypertension (PH‐COPD) was a negative trial that was terminated early.
Steven D. Nathan+7 more
doaj +1 more source
The Effect of Wheat Allergy on the Course of Atopic Eczema in Patients over 14 Years of Age
Few studies concerning the importance of wheat allergy affecting the course of atopic eczema in adolescents and adult patients exist. Aim: The evaluation if wheat allergy can deteriorate the course of atopic eczema.
Jarmila Čelakovská+4 more
doaj +1 more source
Anticholinergic therapy for acute asthma in children. [PDF]
Inhaled anticholinergics as single agent bronchodilators (or in combination with beta(2)-agonists) are one of the several medications available for the treatment of acute asthma in ...
Beakes+49 more
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The use of topical diclofenac in the pain management of osteoarthritis of the knee [PDF]
Osteoarthritis (OA) is a common complaint that affects millions of people worldwide. As there is no cure for OA, drug treatment is the main form of management.
Banning, M
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