Results 51 to 60 of about 8,791 (255)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Seismic Tomography and Earthquake Relocation in North China Craton From 2008 to 2017

Frontiers in Earth Science, 2022
We present a newly developed three-dimensional seismic velocity model and high-precision earthquake relocations in North China using seismic data recorded by the National Earthquake Data Center of China from 2008 to 2017 through the double-difference ...
Bateer Wu, Bateer Wu, Bateer Wu, Bateer Wu, Tian Ma   +4 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Relocation of Moderate-to-small Earthquakes in and Around Hainan Island

CT Lilun yu yingyong yanjiu
In this study, 6090 P-wave and 5545 S-wave arrival time data recorded by 68 seismic stations during 415 seismic events in and around Hainan Island between November 18, 2008, and October 26, 2023, were collected from the China Earthquake Networks Center ...
Yunfei GUO, Jianshe LEI, Penghu GUAN
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Characterization and Cross-Sectional Modeling of the Newly Identified Rawup Fault Based on Relocated Hypocenters and Focal Mechanism in South Sulawesi

Indonesian Journal of Applied Physics
This study presents an integrated seismotectonic analysis combining earthquake hypocenter relocation and P-wave polarity–based focal mechanism modeling to investigate the microseismic cluster in the Maros–Pangkep region, South Sulawesi.
Kevin Hanyu Clinton Wulur, Joshua Purba, Ramadhan Priadi   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spatiotemporal Properties of Seismicity and Variations of Shear-Wave Splitting Parameters in the Western Gulf of Corinth (Greece)

Applied Sciences, 2021
The Western Gulf of Corinth (WGoC) exhibits significant seismicity patterns, combining intense microseismic background activity with both seismic swarms and short-lived aftershock sequences.
Vasilis Kapetanidis, Georgios Michas, George Kaviris, Filippos Vallianatos   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Outer trench slope extension to frontal wedge compression in a subducting plate

Earth, Planets and Space, 2022
The occurrence of faulting in subducting plates is a major process that changes the mechanical properties of the subducting lithosphere and carries surface materials into mantle wedges.
Emmy T. Chang, Laetitia Mozziconacci
doaj   +1 more source