Results 221 to 230 of about 2,222,944 (354)

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Pacioli's De scripturis in the Context of the Spread of Double entry Bookkeeping

, 2017
B. S. Yamey
openalex   +2 more sources

Percutaneous Treatment of Type A Aortic Dissection Using Atrial Septal Defect Occlusion Device. [PDF]

J Cardiovasc Dev Dis
Pintea Bentea G, Morissens M, Massart PE, Castro Rodriguez J.   +3 more
europepmc   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

The Double-Entry Time Trap: Reframing Temporal Distortion as a Perpetuating Mechanism in Addiction

Alessia Baccarani, Quentin Hallez
openalex   +1 more source

The Gracilis Muscle Reappraised: An Integrative Synthesis of Anatomy, Embryology, Imaging, and Surgical Applications. [PDF]

J Clin Med
Landfald IC, Aragonés P, Pilewski D, Olewnik Ł.   +3 more
europepmc   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Incessant Focal Atrial Tachycardia Originating From the Right Inferior Pulmonary Vein With Extremely Short Cycle Length and Variable Exit Block. [PDF]

Case Rep Cardiol
Hayashi H, Sekita G, Minamino T.
europepmc   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Cancellation of principal in banking: Three radical ideas emerge from deep examination of double entry bookkeeping in banking [PDF]

, 2020
Brian P. Hanley
openalex