Results 61 to 70 of about 55,719 (269)

Profound Leadership Strategies: Transcending the Leadership Crisis in the Age of Artificial Intelligence

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley   +1 more source

Colon Drug Delivery Systems Based on Swellable and Microbially Degradable High-Methoxyl Pectin: Coating Process and In Vitro Performance

Pharmaceutics
Oral colon delivery systems based on a dual targeting strategy, harnessing time- and microbiota-dependent release mechanisms, were designed in the form of a drug-containing core, a swellable/biodegradable polysaccharide inner layer and a gastroresistant ...
Saliha Moutaharrik, Luca Palugan, Matteo Cerea, Gabriele Meroni, Eleonora Casagni, Gabriella Roda, Piera Anna Martino, Andrea Gazzaniga, Alessandra Maroni, Anastasia Foppoli   +9 more
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Small molecular weight polyfluoroalkyl phosphonates induce ROS-mediated cytotoxicity in glioblastoma cells: a molecular mechanism study

Scientific Reports
Glioblastoma (GBM) is an aggressive brain tumour with limited treatment options and poor patient survival, largely due to the blood-brain barrier (BBB) restricting effective drug delivery.
Patryk Wołodkiewicz, Michał Juszczak, Paweł Tokarz, Katarzyna Woźniak, Paulina Tokarz   +4 more
doaj   +1 more source

3D THM modelling of Finnish spent nuclear fuel repository

Frontiers in Built Environment
This paper presents modelling of the long-term performance of engineered barrier systems (EBS) in crystalline host rock in terms of coupled thermo-hydro-mechanical (THM) processes in a specific case, considering also the impact of salinity linked with ...
Erdem Toprak, Sebastia Olivella, Sebastia Olivella, Xavier Pintado, Mika Niskanen   +4 more
doaj   +1 more source

Pricing Two-Asset Double Barrier Options Using the Hybrid Method

, 2013
[[abstract]]Barrier options are the most popular derivatives used for hedging or speculating in financial markets, specifically in foreign exchange markets.
Andrew M.L.Wang , Y.L.Hsiao
core  

Alternative models for FX, arbitrage opportunities and efficient pricing of double barrier options in L\'evy models

, 2023
We analyze the qualitative differences between prices of double barrier no-touch options in the Heston model and pure jump KoBoL model calibrated to the same set of the empirical data, and discuss the potential for arbitrage opportunities if the correct ...
Boyarchenko, Svetlana, Levendorskii, Sergei   +1 more
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Pricing and hedging of Asian options: Quasi-explicit solutions via Malliavin calculus [PDF]

, 2011
We use Malliavin calculus and the Clark-Ocone formula to derive the hedging strategy of an arithmetic Asian Call option in general terms. Furthermore we derive an expression for the density of the integral over time of a geometric Brownian motion, which ...
Yang, Z., Olaf Menkens, Menkens, O., Yang, Zhaojun, Menkens, Olaf, Christian-Oliver Ewald, Ewald, C.-O., Zhaojun Yang, Ewald, Christian-Oliver   +8 more
core   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source