Results 91 to 100 of about 3,851,688 (392)

Improvements in Health‐Related Quality of Life With Treat‐to‐Target Urate‐Lowering Therapy in Gout: A Post Hoc Analysis of a Randomized Multicenter Trial

open access: yesArthritis Care &Research, EarlyView.
Objective Although treat‐to‐target urate‐lowering therapy (ULT) is endorsed as best practice in gout management, limited data exist on its impact on health‐related quality of life (HRQoL). We assessed the impact of treat‐to‐target ULT on HRQoL among participants receiving protocolized gout care, identifying factors associated with HRQoL and HRQoL ...
Austin Barry   +16 more
wiley   +1 more source

Experimenter bias across gender differences [PDF]

open access: yes
This paper reports on a laboratory study that examined the influence of experimenter bias in the investment game. Specifically we explored the effect of changing the gender of the experimenter and compared it with the double blind treatment. Our findings
Alessandro Innocenti   +1 more
core  

Cost‐Effectiveness of Low‐Dose Colchicine Prophylaxis When Starting Allopurinol Using the “Start‐Low Go‐Slow” Approach for Gout: Evidence From a Noninferiority Randomized Double‐Blind Placebo‐Controlled Trial

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to investigate the cost‐effectiveness of low‐dose colchicine prophylaxis for preventing gout flares when starting allopurinol using the “start‐low go‐slow” approach. Methods Participants with gout, fulfilling the American College of Rheumatology recommendations for starting urate‐lowering therapy and with serum urate
Yana Pryymachenko   +4 more
wiley   +1 more source

How effective is prophylactic therapy for gout in people with prior attacks? [PDF]

open access: yes, 2004
Colchicine (strength of recommendation [SOR]: B, based on 1 double-blind crossover study), allopurinol (SOR: B, based on 2 cohort studies), and weight loss (SOR: B, based on 1 small cohort study) have been shown to reduce symptomatic recurrences of gout,
Weismantel, Arlene McFarlin   +1 more
core  

Effectiveness and safety of baricitinib for juvenile idiopathic arthritis associated uveitis or chronic anterior antinuclear antibody positive uveitis

open access: yesArthritis Care &Research, Accepted Article.
Objectives Evaluate the efficacy and safety of baricitinib in paediatric patients with active JIA‐U or chronic anterior ANA‐positive uveitis, who had an inadequate response to MTX or bDMARDs. Methods JUVE‐BRIGHT was an open‐label, active‐controlled, Phase‐3 multicentre trial which utilized a novel design, including 1:1 randomization to an active ...
Athimalaipet V. Ramanan   +7 more
wiley   +1 more source

Validación de un nuevo método de acupuntura placebo con potencial doble ciego. Fase II: cegamiento del operador

open access: yesOdontoestomatología
Resumen: Se presenta un nuevo método de acupuntura placebo, evaluándose en esta fase el cegamiento del operador. Metodología: Se implementaron dos estudios experimentales utilizando como referencia el punto acupuntural Intestino Grueso 4 (IG4).
Alejandro Francia   +3 more
doaj   +1 more source

Aspartame sensitivity? A double blind randomised crossover study.

open access: yesPLoS ONE, 2015
BackgroundAspartame is a commonly used intense artificial sweetener, being approximately 200 times sweeter than sucrose. There have been concerns over aspartame since approval in the 1980s including a large anecdotal database reporting severe symptoms ...
Thozhukat Sathyapalan   +10 more
doaj   +1 more source

Double-blind test program for astrometric planet detection with Gaia

open access: yes, 2008
We use detailed simulations of the Gaia observations of synthetic planetary systems and develop and utilize independent software codes in double-blind mode to analyze the data, including statistical tools for planet detection and different algorithms for
A. Sozzetti   +133 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

Hammers and blind man’s sticks: re-examining the digital double [PDF]

open access: yes
This presentation draws on my research in to technological embodiment as part of my PhD studies, which explores a phenomenon called the ‘digital double’ – a manipulable representation of the human body in a variety of performance and new media contexts ...
Preece, Kelly Louise
core  

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