Results 191 to 200 of about 1,233,954 (328)
This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao+7 more
wiley +1 more source
Comparison of inhalation and total intravenous anesthesia on inflammatory markers in microdiscectomy: a double-blind study. [PDF]
Yediyıldız MB+7 more
europepmc +1 more source
This study uncovers CHKA as a pivotal driver of vascular dysfunction in diabetic retinopathy and highlights its role in endothelial dysfunction through NAD⁺‐SIRT1‐Notch signaling. Single‐cell and functional analyses, combined with clinical and genetic validation, suggest CHKA as a promising therapeutic target for the prevention and treatment of ...
Ling Ren+11 more
wiley +1 more source
The Effect of Probiotics on Health in Pregnancy and Infants: A Randomized, Double-Blind, Placebo-Controlled Trial. [PDF]
Binda S+9 more
europepmc +1 more source
Double-blind evaluation of mazindol in refractory obesity. [PDF]
R. G. Smith+2 more
openalex +1 more source
Microphysiological Uremia Model Reveals Biophysical Potentiators of Vascular Dysfunction
A microfluidic platform of engineered blood vessels is developed to study the role of mechanical forces in immune cell adhesion and extravasation in uremic microenvironments. Elevated pressure increases monocyte activity, with ICAM‐1 as a key driver. Matrix density influences monocyte phenotypes, but the uremic environment consistently promoted a pro ...
Mitesh Rathod+9 more
wiley +1 more source