Efficacy and safety of perampanel in patients with drug-resistant partial seizures after conversion from double-blind placebo to open-label perampanel [PDF]
, 2015 SummaryObjectiveTo evaluate the efficacy and safety of perampanel in patients with drug-resistant partial seizures after the conversion from double-blind placebo in three phase III studies to open-label perampanel, and to assess the impact of perampanel ...
Fain, Randi +5 more
core +1 more source
Attitudes toward open peer review among stakeholders of a scholar-led journal in Brazil
Transinformação, 2021 Scholarly journals should consider the attitudes of their communities before adopting any of the seven traits of open peer review. Unfortunately, surveys from the Global North might not apply to the Global South, where double-blind peer review is ...
Leonardo Ferreira Fontenelle +1 more
doaj +1 more source
FEBS Letters, Volume 599, Issue 7, Page 1075-1085, April 2025.We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti +2 more
wiley +1 more source
Sublingual Immunotherapy with House Dust Extract for House Dust-Mite Allergic Rhinitis in Children
Allergology International, 2010 Background: House dust extract is used in conventional immunotherapy for house dust-mite (HDM) allergic rhinitis in Japan. However, an alternative administration route is desired.
Syuji Yonekura +11 more
doaj +1 more source
Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in acute lung injury to reduce pulmonary dysfunction (HARP-2) trial : study protocol for a randomized controlled trial [PDF]
, 2012 Acute lung injury (ALI) is a common devastating clinical syndrome characterized by life-threatening respiratory failure requiring mechanical ventilation and multiple organ failure.
A Mercat +31 more
core +1 more source
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
Frontiers in Veterinary ScienceIntroductionCannabinoids show great therapeutic potential, but their effect on anesthesia still remains unclear. Use of chronic recreational Cannabis in humans undergoing anesthetic procedures tends to require a higher dose when compared to non-users. On
João Lourenço Hasckel Gewehr +8 more
doaj +1 more source
Towards Flexible Blind JPEG Artifacts Removal [PDF]
arXiv, 2021 Training a single deep blind model to handle different quality factors for JPEG image artifacts removal has been attracting considerable attention due to its convenience for practical usage. However, existing deep blind methods usually directly reconstruct the image without predicting the quality factor, thus lacking the flexibility to control the ...
arxiv
Acoustic Echo and Noise Cancellation System for Hand-Free Telecommunication using Variable Step Size Algorithms [PDF]
, 2013 In this paper, acoustic echo cancellation with doubletalk detection system is implemented for a hand-free telecommunication system using Matlab. Here adaptive noise canceller with blind source separation (ANC-BSS) system is proposed to remove both ...
Chandra, M., Gupta, V. K., Sharan, S. N.
core +1 more source
Cognitive Bias in Line-Up Identifications: The Impact of Administrator Knowledge [PDF]
, 2012 Prior knowledge of the likely or expected outcome of a forensic investigation has been shown to produce biases in the results obtained, reducing objectivity.
Canter, David V. +2 more
core +1 more source