Results 61 to 70 of about 1,217,627 (297)

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Sequential double quantum blind signature protocol

Tongxin xuebao, 2015
Considering the fact that both party banks need to sign on the same bill because of the inter-bank E-payment in real life.A sequential double blind signature protocol based on the quantum coherence and quantum entanglement was proposed for the first time.
Hui WANG, Run-hua SHI, Hong ZHONG, Jie CUI, Shun ZHANG, Kai-ting WANG   +5 more
doaj   +2 more sources

Behavioural and neuroplastic effects of a double-blind randomised controlled balance exercise trial in people with Parkinson’s disease

npj Parkinson's Disease, 2022
Balance dysfunction is a disabling symptom in people with Parkinson’s disease (PD). Evidence suggests that exercise can improve balance performance and induce neuroplastic effects.
Malin Freidle, Hanna Johansson, Urban Ekman, Alexander V. Lebedev, Ellika Schalling, William H. Thompson, Per Svenningsson, Martin Lövdén, Alonso Abney, Franziska Albrecht, Hanna Steurer, Breiffni Leavy, Staffan Holmin, Maria Hagströmer, Erika Franzén   +14 more
doaj   +1 more source

Rethinking clinical trials of transcranial direct current stimulation: Participant and assessor blinding is inadequate at intensities of 2mA [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
Benedict M. Wand, David Bunce, G. Lorimer Moseley, John Cossar, Lorraine H. De Souza, Louise Marston, Neil E. O’Connell, Sam Eldabe   +7 more
core   +3 more sources

Clinically Relevant Outcome Measures in Women With Adrenoleukodystrophy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Adrenoleukodystrophy is a rare inherited peroxisomal disease caused by pathogenic variants in the ABCD1 gene located on the X chromosome. Although the most severe central nervous system and adrenal complications typically affect only men with adrenoleukodystrophy, the majority of women develop myeloneuropathy symptoms in adulthood.
Chenwei Yan, Elizabeth I. Pierpont, Amena S. Fine, Reena V. Kartha   +3 more
wiley   +1 more source

How to maintain the maximal level of blinding in randomisation for a placebo-controlled drug trial

Contemporary Clinical Trials Communications, 2019
We illustrate the approach of randomising treatments and compare it with the traditional approach of randomising patients, using a case study drawn from the authors’ experience in clinical trials. The setting is a double-blind parallel two-arm randomised
Lei Clifton, David A. Clifton
doaj   +1 more source

Impact of Asymptomatic Intracranial Hemorrhage on Outcome After Endovascular Stroke Treatment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Endovascular treatment (EVT) achieves high rates of recanalization in acute large‐vessel occlusion (LVO) stroke, but functional recovery remains heterogeneous. While symptomatic intracranial hemorrhage (sICH) has been well studied, the prognostic impact of asymptomatic intracranial hemorrhage (aICH) after EVT is less certain ...
Shihai Yang, Chengsong Yue, Zhuang Li, Xiaolei Shi, Haoxuan Zhu, Jie Yang, Linyu Li, Jiaxing Song, Shitao Fan, Gaoming Li, Wenzhe Sun, Zhixian Ye, Jiacheng Huang, Dahong Yang, Jinfu Ma, Xu Xu, Zhixi Wang, Lilan Wang, Guojian Liu, Fengli Li, Changwei Guo, Li Qi, Wenjie Zi   +22 more
wiley   +1 more source

Double-blind acupuncture needles: a multi-needle, multi-session randomized feasibility study

Pilot and Feasibility Studies, 2018
Background Efficacy of acupuncture is difficult to demonstrate without a feasible double-blind milieu. Double-blind acupuncture needles have been validated in single session protocols with one or two needles but not been tested in a protocol requiring ...
Judith M. Schlaeger, Nobuari Takakura, Hiroyoshi Yajima, Miho Takayama, Alana D. Steffen, Elizabeth M. Gabzdyl, Robyn A. Nisi, Kathleen McGowan Gruber, Jason M. Bussell, Diana J. Wilkie   +9 more
doaj   +1 more source

Double-blind test program for astrometric planet detection with Gaia

, 2008
We use detailed simulations of the Gaia observations of synthetic planetary systems and develop and utilize independent software codes in double-blind mode to analyze the data, including statistical tools for planet detection and different algorithms for
A. Sozzetti, A. Spagna, Agol, Alibert, Armitage, Bakos, Baraffe, Barnes, Bean, Beaulieu, Benedict, Benedict, Bienaymé, Biller, Bond, Bonfils, Boss, Boss, Boss, Boss, Boss, Bouchy, Bouchy, Burrows, Burrows, Butler, Butler, Casertano, Catanzarite, Chauvin, Chauvin, Collier Cameron, Correia, D. Pourbaix, D. Queloz, de Felice, de Felice, de Felice, Des Marais, Dyudina, Endl, Eriksson, Fischer, Fischer, Ford, Ford, Ford, Frink, Galland, Gaudi, Gould, Gozdziewski, Hatzes, Hitchcock, Holman, Horne, Hubbard, Ida, Ida, Ida, Ida, Ji, Johnson, Johnson, Johnson, Jones, Kaltenegger, Kasting, Kiseleva-Eggleton, Klioner, Klioner, Klioner, Konacki, Konacki, Konacki, Kornet, Kornet, Kornet, Kovács, Lattanzi, Laughlin, Laughlin, Lindegren, Livio, Lovis, Lovis, López-Santiago, M. G. Lattanzi, Mandushev, Marcy, Mayer, Mayor, McArthur, Menou, Miralda-Escudé, Neuhäuser, Niedzielski, Pepe, Perryman, Perryman, Pollack, Pont, Pourbaix, R. Morbidelli, R. Pannunzio, Rice, Rice, Rivera, Robin, S. Casertano, S. Jancart, Santos, Sato, Seager, Selsis, Setiawan, Setiawan, Sozzetti, Sozzetti, Sozzetti, Sozzetti, Sozzetti, Sudarsky, Tabachnik, Takeuchi, Thommes, Tinetti, Udalski, Udry, Unwin, Vecchiato, von Bloh, Wright, Zuckerman   +133 more
core   +1 more source

Efficacy of Intermittent Theta‐Burst Stimulation for Prolonged Disorders of Consciousness: A Prospective, Randomized, Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Emerging evidence suggests that low‐frequency neural oscillations are dynamically regulated by consciousness levels, with the recovery of low cortical activity potentially serving as a neurophysiological substrate for conscious emergence. Targeted enhancement of these low‐frequency rhythms in patients with disorders of consciousness
Chuan Xu, Jun Hu, Qianqian Wu, Min Wu, Yamei Yu, Hangcheng Li, Jian Gao, Jingqi Li, Nai Ding, Jie Yu, Benyan Luo   +10 more
wiley   +1 more source