On the sampling strategies and models for measuring diffusion exchange with a double diffusion encoding sequence [PDF]
Magnetic Resonance Letters, 2023 Water exchange between the different compartments of a heterogeneous specimen can be characterized via diffusion magnetic resonance imaging (dMRI). Many analysis frameworks using dMRI data have been proposed to describe exchange, often using a double ...
Alfredo Ordinola +4 more
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Mapping complex cell morphology in the grey matter with double diffusion encoding MR: A simulation study [PDF]
NeuroImage, 2021 This paper investigates the impact of cell body (namely soma) size and branching of cellular projections on diffusion MR imaging (dMRI) and spectroscopy (dMRS) signals for both standard single diffusion encoding (SDE) and more advanced double diffusion ...
A. Ianus +3 more
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Brain White-Matter Degeneration Due to Aging and Parkinson Disease as Revealed by Double Diffusion Encoding [PDF]
Frontiers in Neuroscience, 2020 Microstructure imaging by means of multidimensional diffusion encoding is increasingly applied in clinical research, with expectations that it yields a parameter that better correlates with clinical disability than current methods based on single ...
Kouhei Kamiya +14 more
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Optimizing Filter-Probe Diffusion Weighting in the Rat Spinal Cord for Human Translation [PDF]
Frontiers in Neuroscience, 2017 Diffusion tensor imaging (DTI) is a promising biomarker of spinal cord injury (SCI). In the acute aftermath, DTI in SCI animal models consistently demonstrates high sensitivity and prognostic performance, yet translation of DTI to acute human SCI has ...
Matthew D. Budde +5 more
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Resolving degeneracy in diffusion MRI biophysical model parameter estimation using double diffusion encoding. [PDF]
Magn Reson Med, 2019 Purpose: Biophysical tissue models are increasingly used in the interpretation of diffusion MRI (dMRI) data, with the potential to provide specific biomarkers of brain microstructural changes.
Coelho S +4 more
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NeuroImage, 2021 Double diffusion encoding (DDE) of the water signal offers a unique ability to separate the effect of microscopic anisotropic diffusion in structural units of tissue from the overall macroscopic orientational distribution of cells.
Henrik Lundell +5 more
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Diffusion MRI with double diffusion encoding and variable mixing times disentangles water exchange from transient kurtosis [PDF]
Scientific ReportsDouble diffusion encoding (DDE) makes diffusion MRI sensitive to a wide range of microstructural features, and the acquired data can be analysed using different approaches.
Arthur Chakwizira +2 more
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NeuroImage, 2020 Brain metabolites, such as N-acetylaspartate or myo-inositol, are constantly probing their local cellular environment under the effect of diffusion. Diffusion-weighted NMR spectroscopy therefore presents unparalleled potential to yield cell-type specific
Mélissa Vincent +2 more
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Frontiers in Physics, 2018 Mapping tissue microstructure accurately and noninvasively is one of the frontiers of biomedical imaging. Diffusion Magnetic Resonance Imaging (MRI) is at the forefront of such efforts, as it is capable of reporting on microscopic structures orders of ...
Noam Shemesh
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Multidimensional encoding of restricted and anisotropic diffusion by double rotation of the q vector [PDF]
Magnetic Resonance, 2023 Diffusion NMR and MRI methods building on the classic pulsed gradient spin-echo sequence are sensitive to many aspects of translational motion, including time and frequency dependence (“restriction”), anisotropy, and flow, leading to ambiguities when ...
H. Jiang, L. Svenningsson, D. Topgaard
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