Results 71 to 80 of about 1,380,032 (300)

Einstein's Photon Concept Quantified by the Bohr Model of the Photon

open access: yes, 2005
The photon is modeled as a monochromatic solution of Maxwell's equations confined as a soliton wave by the principle of causality of special relativity. The soliton travels rectilinearly at the speed of light.
Alexandrescu, Camil   +2 more
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Online cable fault ranging method by double-end traveling wave for underground distribution network

open access: yesGong-kuang zidonghua, 2016
In order to solve problems of block overlap of frequency bands in cable fault ranging method based on empirical mode decomposition and effect of residual white noise in the one based on ensemble empirical mode decomposition, an online cable fault ranging
ZHAO Min, SHANG Penghui
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

open access: yesFEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada   +5 more
wiley   +1 more source

The principle of double effect and medical ethics. [PDF]

open access: yesBMJ, 1986
KIE: In one of a series of articles on philosophical medical ethics, Gillon examines the Roman Catholic doctrine of double effect as it applies to discussions of the moral difference between acts and omissions in patient care. The doctrine holds that, in the context of actions that have both good and bad effects, an action that has a bad effect is ...
openaire   +2 more sources

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

EL PRINCIPIO DEL DOBLE EFECTO Y SU RELEVANCIA EN EL RAZONAMIENTO JURÍDICO THE DOUBLE EFFECT PRINCIPLE AND ITS RELEVANCE TO JURIDICAL INTERPRETATION

open access: yesRevista Chilena de Derecho, 2008
En este trabajo el autor intenta mostrar la relevancia que le corresponde al principio del doble efecto en el razonamiento práctico general y especialmente en el razonamiento jurídico. Para ello procede del siguiente modo.
Alejandro Miranda Montecinos
doaj  

Double Sided Lapping/Polishing Machine Grinding Trajectory Studies

open access: yesJournal of Harbin University of Science and Technology, 2018
In this paper,by analyzing the double-sided lapping /polishing processing mechanism,the stress analysis was carried out on the workpiece,and we establish the pads relatively workpiece in machining the movement principle of trajectory model,pads,relative ...
XU Li   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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