Results 51 to 60 of about 208,180 (267)
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
A Study on Water Model for Optimum Process of Bottom Blowing Argon of 120 t Ladle
Teshugang, 2017 Based on the principle of similarity, a water model with geometric similarity ： 3 for 120 t ladle in steel is established. The effect of argon conditions of single and double porous brick ( porous location, blowing gas rate 0. 4 ~ 2.
张真铭 +5 more
doaj
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Online cable fault ranging method by double-end traveling wave for underground distribution network
Gong-kuang zidonghua, 2016 In order to solve problems of block overlap of frequency bands in cable fault ranging method based on empirical mode decomposition and effect of residual white noise in the one based on ensemble empirical mode decomposition, an online cable fault ranging
ZHAO Min, SHANG Penghui
doaj +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Revista Chilena de Derecho, 2008 En este trabajo el autor intenta mostrar la relevancia que le corresponde al principio del doble efecto en el razonamiento práctico general y especialmente en el razonamiento jurídico. Para ello procede del siguiente modo.
Alejandro Miranda Montecinos
doaj
Directed evolution of enzymes at the crossroads of tradition and innovation
FEBS Open Bio, EarlyView.An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source
Double Sided Lapping/Polishing Machine Grinding Trajectory Studies
Journal of Harbin University of Science and Technology, 2018 In this paper，by analyzing the double-sided lapping /polishing processing mechanism，the stress analysis was carried out on the workpiece，and we establish the pads relatively workpiece in machining the movement principle of trajectory model，pads，relative ...
XU Li +4 more
doaj +1 more source