Results 141 to 150 of about 3,960,683 (297)

Androgen-deprivation therapy and SARS-Cov-2 infection: the potential double-face role of testosterone. [PDF]

Ther Adv Endocrinol Metab, 2020
Salciccia S, Del Giudice F, Eisenberg ML, Mastroianni CM, De Berardinis E, Ricciuti GP, Maggi M, Sciarra A.   +7 more
europepmc   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

The double face of miR-320: cardiomyocytes-derived miR-320 deteriorated while fibroblasts-derived miR-320 protected against heart failure induced by transverse aortic constriction. [PDF]

Signal Transduct Target Ther, 2021
Zhang X, Yuan S, Li H, Zhan J, Wang F, Fan J, Nie X, Wang Y, Wen Z, Chen Y, Chen C, Wang DW.   +11 more
europepmc   +1 more source

Case of Double Zoster of the Face in a Schoolboy [PDF]

Proceedings of the Royal Society of Medicine, 1909
openaire   +2 more sources

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

Molecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David, Arthur Karaulic, Audrey Bennetot, Clémence Fournier, Quentin Odet, Arthur Gouraud, Isabelle Bourget, Cédric Gaggioli, Sandy Giuliano, Frédéric Luciano, Olivier Léger, Zaki Sellam, Gilles Pagès   +12 more
wiley   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Advanced Recital: David Malone, double bass

, 2008
This recital is given in partial fulfillment of the requirements for the degree Master of MusicMr. Malone is a student of Paul Ellison.Sonata No. 3 in G Minor for Viola da Gamba, Johann Sebastian Bach (1685-1750) -- Duets for Double Basses (1966), Frank ...

core  

Gas migration control in goaf with double roof cutting and retaining roadway

Scientific Reports
The behavior of gas migration in goaf under double roof cutting conditions directly influences the effectiveness of gas control measures. This study employs a combination of numerical simulation and field verification to investigate the patterns of gas ...
Xiaobo Lv, Shengyong Hu, Jun Nian, Chunsheng Deng, Bo Zhao, Cheng He, Yansheng Wang, Xitu Zhang, Wei Zhang   +8 more
doaj   +1 more source

The multifaceted roles of lysosomes in cancer

Molecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

David R. Malone, double bass; Brenda Landrum, keyboard

, 2008
Sonata No. 1, Johann Sebastian Bach (1685-1750) -- Concerto in E Major, Karl Ditters von Dittersdorf (1739-1799) -- Two Pieces for Double Bass, Charles Hoag -- Three Pieces, Reinhold Morit͡sevich Glière (1875 ...

core