Results 81 to 90 of about 1,519 (199)

A cryptic allosteric pocket shapes isoform‐selective inhibition of human malic enzymes

Protein Science, Volume 35, Issue 9, September 2026.
Abstract Malic enzymes (ME) regulate central carbon metabolism and cellular redox balance, and the mitochondrial isoform ME2 is frequently upregulated in aggressive cancers to support metabolic flexibility and stress resistance. Isoform‐selective inhibition has remained out of reach because the catalytic machinery is essentially invariant across the ...
Ben A. Krinkel, Yuliana Yosaatmadja, Mark D. Slayton, Anita Krinkel, Jack Copping, Jin Heon Jeon, Joyce Eu, Kerslee Kohagen, Amir Ashoorzadeh, Jeff Smaill, Jack Flanagan, Christopher Walker, Sofia D. Merajver, Kerry Loomes, Christopher J. Squire   +14 more
wiley   +1 more source

A Systematic Review and Taxonomy of Fall Detection in Geriatric Care: Current State, Challenges, and Applications

WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 3, September 2026.
Overview of fall‐detection approaches and technologies in geriatric care. ABSTRACT This systematic review provides a critical examination of fall detection (FD) technologies in geriatric care, analyzing both technological innovations and implementation challenges across diverse healthcare environments.
Hamid Ali, Ji Zhang, Xiaohui Tao, Raj Gururajan, Xujuan Zhou, Yuquan Gan, Josh Jia‐Ching Ying   +6 more
wiley   +1 more source

Activity and Habitat Selection of an Apex Predator in Semi‐Arid Rangeland Production Areas: Implications for Optimising Management Efforts

Ecological Management &Restoration, Volume 27, Issue 3, September 2026.
ABSTRACT In the complex interplay between agriculture and wildlife, free‐living predators pose a unique set of challenges. In western New South Wales (NSW), free‐living canids (legislatively defined as ‘wild dogs’; Canis familiaris; which currently includes dingoes, feral modern dogs and their hybrids) are managed due to their impacts on livestock ...
Deane Smith, Paul D. Meek, Lucy Collingridge, Bruce Duncan, Guy Ballard, Peter J. S. Fleming   +5 more
wiley   +1 more source

Bloom filters for molecules. [PDF]

J Cheminform, 2023
Medina J, White AD.
europepmc   +1 more source

Intentionality and Attentionality Dynamics in an Institutional Change Process

Journal of Management Studies, Volume 63, Issue 6, Page 2700-2731, September 2026.
Abstract In this article, we explore how actors' intentionality emerges, develops, and co‐evolves with institutional change. Although intentions are essential in shaping institutional change agents' motivations and actions, our understanding of their dynamics is limited and biased by the assumption that intentions are usually identifiable prior to ...
Sofiane Baba, Taïeb Hafsi, Omar Hemissi
wiley   +1 more source

Pragmatism, Dual‐Process Theory, and the Study of Reflective Cognition

Journal for the Theory of Social Behaviour, Volume 56, Issue 3, September 2026.
ABSTRACT This article advances dual‐process theory (DPT) by developing a pragmatist framework for the study of reflective cognition. Although dual‐process models were introduced to sociology via Bourdieusian practice theory, Bourdieusian DPT has proven inadequate for theorising reflective cognition and action, with sociologists looking to pragmatism as
Gordon Brett
wiley   +1 more source

Evaluating Extraction of Magnesium and Lithium Compounds from Seawater Using Byproducts of Demonstration‐Scale Bipolar Membrane Electrodialysis

ChemSusChem, Volume 19, Issue 16, 27 August 2026.
Integrating multiple seawater‐based processes could improve efficiency and reduce process costs. Here, we assess combining mineral extraction with a demonstration‐scale bipolar membrane electrodialysis (BPMED) unit. Acid and base streams from BPMED are used for lithium and magnesium recovery from seawater, presenting a sustainable method for marine ...
Qingpu Wang, Elisabeth A. Ryan, Paul G. Marsh, Peter J. Valdez, Chinmayee V. Subban   +4 more
wiley   +1 more source

Development and validation of an automated evaluation system for lattice radiotherapy using a commercial treatment planning system scripting API

Journal of Applied Clinical Medical Physics, Volume 27, Issue 8, August 2026.
Abstract Purpose Clinical implementation of lattice radiotherapy (LRT) remains constrained by the absence of standardized, automated tools for comprehensive post‐plan dosimetric analysis within commercial treatment planning systems (TPS). Herein, an automated script‐based tool was developed using the Eclipse Scripting API (ESAPI) to enable rapid ...
Xingliu Wang, Ruifeng Zhao, Yongqiang Li, Qinghua Xu   +3 more
wiley   +1 more source

Acute and Chronic Effects of Aerobic Exercise on Motor Inhibition and Cortical Excitability in Adolescents With Attention Deficit Hyperactivity Disorder

Brain and Behavior, Volume 16, Issue 8, August 2026.
In adolescents with ADHD, acute and chronic aerobic exercise enhance motor inhibition. Chronic exercise yields greater benefits and reduces cortical excitability, linking behavioral gains to neurophysiological changes. These findings support sustained exercise as a therapeutic strategy for improving inhibitory control.
Jia‐Ling Sun, Jung‐Chi Chang, Pou‐Leng Cheong, Hsiao‐I Kuo   +3 more
wiley   +1 more source

Superior Cardiorenal Protection With Tirzepatide Over Dulaglutide in Heart Failure With Preserved Ejection Fraction: A Large‐Scale Propensity Score–Matched Real‐World Analysis

Clinical Cardiology, Volume 49, Issue 8, August 2026.
In this large real‐world propensity‐matched analysis, tirzepatide demonstrated superior reductions in mortality, hospitalizations, and cardiorenal outcomes versus dulaglutide in HFpEF patients, with a favorable safety profile. ABSTRACT Background No direct head‐to‐head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection ...
Ibrahim Khalil, Md. Imran Hossain, Mst. Mahmuda Akter, Ferdous Wahid, Aizaz Anwar Khalid, Sunjida Amin Promi, Md. Abu Sayed, Mohd Turzo Rahman, Pallab Sarker   +8 more
wiley   +1 more source