Results 111 to 120 of about 10,952,065 (350)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

From SRI to ESG: The Changing World of Responsible Investing [PDF]

open access: yes, 2013
The terms socially-responsible investing (SRI), mission-related investing, impact investing and environmental, social and governance (ESG) investing -- all frequently grouped under the heading of responsible investing -- have become a familiar part of ...
Lauren Caplan
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Material, Trace, Trauma: Notes on some Recent Acquisitions at the Canadian War Museum and the Legacy of the First World War [PDF]

open access: yes, 2017
Recent acquisitions at the Canadian War Museum are considered in relation to the radical innovations of soldier-artists who endured the somatic conditions of the First World War trenches, privileging materiality and psychic reality over visual perception.
Conley, Christine
core   +1 more source

Verses of Faith and Devotion. Seeing, Reading, and Touching Monumental Crucifixes with Inscriptions (12th–13th century) [PDF]

open access: yes, 2016
The paper discusses a group of monumental crucifixes from the 13th-century East Adriatic and Italy, pained or executed in low relief, that display a verse inscriptions on the transverse limb of the cross.
Marušić, Matko Matija
core   +1 more source

Layered double hydroxide/sepiolite heterostructured materials

open access: yesApplied Clay Science, 2016
Oral presentation given at the Euroclay 2015, held in Edinburgh (Scotland), on July 5-10th, 2015.
Gómez Avilés, Almudena   +2 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

La materialidad de la memoria en Las cartas que no llegaron de Mauricio Rosencof (Uruguay, 1930-2000).

open access: yesHistoria Crítica, 2010
This article examines the way that Uruguayan author Mauricio Rosencof reconstructs family genealogy and self identity in Las cartas que no llegaron.
Anna Forné.
doaj  

Harsh Poetry and Art's Address: Romare Bearden and Hans-Georg Gadamer in Conversation [PDF]

open access: yes, 2016
In this essay, I analyze Romare Bearden’s art, methodology, and thinking about art, as well as his attempt to harmonize his personal aesthetic goals with his sociopolitical concerns.
Nielsen, Cynthia R.
core  

Double-negative-index ceramic aerogels for thermal superinsulation

open access: yesScience, 2019
Elastic ceramics Aerogels hold promise as lightweight replacements for thermal insulation. However, poor mechanical stability has hampered progress in moving toward commercialization. Xu et al.
Xiang Xu   +25 more
semanticscholar   +1 more source

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