Results 111 to 120 of about 79,920 (305)
From SRI to ESG: The Changing World of Responsible Investing [PDF]
, 2013 The terms socially-responsible investing (SRI), mission-related investing, impact investing and environmental, social and governance (ESG) investing -- all frequently grouped under the heading of responsible investing -- have become a familiar part of ...
Lauren Caplan
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Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Digitally Yours; The Body in Contemporary Photography [PDF]
, 2009 This article analyses two artworks by contemporary photographers, Alexa Wright and Wendy McMurdo. It focuses in particular on the relationship between digital technologies and representation of the body, and on the changes to accepted paradigms of ...
Rubinstein, Daniel
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Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Materiality, Parthood, and Possibility [PDF]
This paper offers an argument in favour of a Lewisian version of concretism that maintains both the principle of material inheritance (according to which, if all the parts of an object x are material, then x is material) and the materiality-modality link
Iaquinto, Samuele, Torrengo, Giuliano
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No TV for Woodpeckers by Gary Barwin, If Pressed by Andrew McEwan, and Ecology without Culture: Aesthetics for a Toxic World by Christine L. Marran [PDF]
, 2018 Review of Gary Barwin\u27s No TV for Woodpeckers, Andrew McEwan\u27s If Pressed, and Christine L.
Sloane, Michael D
core +1 more source
Dumping Dredged Material with Double-Tremie
PROCEEDINGS OF CIVIL ENGINEERING IN THE OCEAN, 1997 Double-tremie work was applied to mitigate some effects caused by dumping dredged materials. Field investigations were carried out in order to clarify its efficiency, which can reduce the discharge of suspended solids by circulating water body in it.
Kenichi Okumura +5 more
openaire +2 more sources
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Sociomateriality and disabled individuals’ identity work: a critical poststructuralist research agenda [PDF]
, 2013 This paper responds to calls to rebalance the role of materiality in identity work. Taking a critical poststructuralist approach to identity work and a relational ontology perspective on sociomateriality, we explore how a ‘disabled’ person’s identity ...
Corlett, Sandra +2 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source