Results 151 to 160 of about 1,857 (290)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Assurance in the Era of CSRD:Opening the black box of double materiality

open access: yes
Third-party assurance has long helped organizations enhance the credibility of sustainability disclosures. With the Corporate Sustainability Reporting Directive (CSRD), assurance is now mandatory for all in-scope companies and must include double ...
Bundgaard, Anja Marie   +2 more
core  

Sustainability reporting under the EU’s new directive. Conducting a double materiality analysis [PDF]

open access: yes
Sustainability reporting has evolved drastically, especially in recent years, moving from voluntary reporting to legal obligations. Businesses must now report on sustainability in accordance with the new EU Directive on corporate sustainability reporting
Silaskivi, Emma
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

Attending to Gyn-Ecology: Managing the 'Mess' of Recurrent Vulvovaginal Thrush. [PDF]

open access: yesSociol Health Illn
Ford T   +4 more
europepmc   +1 more source

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

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