Results 41 to 50 of about 1,417,435 (243)

A bidirectional Optimality Theoretic analysis of multiple negative indefinites in Afrikaans

open access: yesStellenbosch Papers in Linguistics, 2014
In the literature on negation, Afrikaans is generally categorised as a negative concord language. Unlike most other negative concord languages though, utterances containing multiple indefinites in the scope of negation are typically produced with a ...
Huddlestone, Kate, de Swart, Henriëtte
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Punk rock as popular theatre [PDF]

open access: yes, 2007
Punk rock performance consciously draws on popular theatre forms like music hall and stand-up comedy, as exemplified by the occasion when Max Wall appeared with Ian Dury at the Hammersmith Odeon.
Double, Oliver
core   +1 more source

Jespersen's cycle in Slovenian

open access: yesLinguistica, 2011
The paper examines the syntactic status of the negative marker in standard Slovenian and its Pannonian dialects in terms of the grammaticalisation process known as Jespersen's cycle.
Gašper Ilc
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Hybrid Negation: Enhancing Sentiment Analysis for Complex Sentences

open access: yesApplied Sciences
Numerous valuable information is available on the Internet, and many individuals rely on mass media as their primary source of information. Various views, comments, expressions, and opinions on social networks have been a tremendous source of information.
Miftahul Qorib, Paul Cotae
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Negation, 'presupposition' and the semantics/pragmatics distinction [PDF]

open access: yes, 1998
A cognitive pragmatic approach is taken to some long-standing problem cases of negation, the so-called presupposition denial cases. It is argued that a full account of the processes and levels of representation involved in their interpretation typically ...
Carston, R
core  

The space of measurement outcomes as a spectrum for non-commutative algebras [PDF]

open access: yesElectronic Proceedings in Theoretical Computer Science, 2010
Bohrification defines a locale of hidden variables internal in a topos. We find that externally this is the space of partial measurement outcomes. By considering the double negation sheafification, we obtain the space of measurement outcomes which ...
Bas Spitters
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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