Results 51 to 60 of about 1,417,435 (243)
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
On negation in yes/no questions in Serbo-Croatian [PDF]
, 2006 The phenomenon discussed in this paper is the so-called expletive negation in negated yes/no questions in Serbo-Croatian. The term expletive negation seems, at this point to be a useful descriptive term for the phenomenon in question. One of the goals of
Milićević, N., Milicevic, Natasa
core
, 2023 According to the law of the excluded middle (hereafter ‘LEM’) any sentence of the form ‘p or not p’ is logically true. In other words, no matter how the work is like in itself, any sentence of this form must be true. Yet the truth of this theorem remains
Sahota, Jagmeet
core
A type system for Continuation Calculus [PDF]
Electronic Proceedings in Theoretical Computer Science, 2014 Continuation Calculus (CC), introduced by Geron and Geuvers, is a simple foundational model for functional computation. It is closely related to lambda calculus and term rewriting, but it has no variable binding and no pattern matching.
Herman Geuvers +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Negation in vernacular Brazilian Portuguese [PDF]
, 2013 textAs Haegeman and Zanuttini (1996:117) discuss, when two negative elements are present in a specific syntactic domain, two possible situations may arise: "(i) the two negative elements may cancel each other out, or (ii) the two elements may ...
Martínez, Cristina, active 2003
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Eye-movements and ERPs reveal the time course of processing negation and remitting counterfactual worlds [PDF]
, 2008 The ability to update our current knowledge using contextual information is a vital process during every-day language comprehension. To understand a negated statement, readers are required to cancel real-world expectations, but are not explicitly ...
Ferguson, Heather J. +2 more
core +1 more source
The Problems of the Mental Logic with the Double Negation: The Necessity of a Semantic Approach
Studies in Logic, Grammar and Rhetoric, 2016 The double negation has always been considered by the logical systems from ancient times to the present. In fact, that is an issue that the current syntactic theories studying human reasoning, for example, the mental logic theory, address today. However,
López-Astorga Miguel
doaj +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source