Results 51 to 60 of about 1,455,426 (270)

The Anaerobic Capacity of Cross-Country Skiers: The Effect of Computational Method and Skiing Sub-technique

open access: yesFrontiers in Sports and Active Living, 2020
Anaerobic capacity is an important performance-determining variable of sprint cross-country skiing. Nevertheless, to date, no study has directly compared the anaerobic capacity, determined using the maximal accumulated oxygen deficit (MAOD) method and ...
Erik P. Andersson   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Pacing, Exercise Intensity, and Technique by Performance Level in Long-Distance Cross-Country Skiing

open access: yesFrontiers in Physiology, 2020
IntroductionLong-distance cross-country skiing (XCS) has gained increased popularity within the past decades. However, research about long-distance XCS is limited; therefore, the aim of this study was to analyze the intensity distribution, technique ...
Thomas L. Stöggl   +6 more
doaj   +1 more source

An Investigation into the Role of Capping on Second Harmonic Generation from Nonlinear Organic Polymer and Guest-Host Thin Films by In-situ Poling [PDF]

open access: yes, 2016
In attempts to fabricate thermally stable second-order nonlinear polymer thin films, we have investigated the second harmonic generation (SHG) from both nonlinear polymer and guest-host thin films. We have also investigated the role of capping on the SHG,
Ushasree, P.M.   +2 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

High-precision geometry of a double-pole pulsar [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 2008
High time resolution observations of PSR B0906-49 (or PSR J0908-4913) over a wide range of frequencies have enabled us to determine the geometry and beam shape of the pulsar. We have used the position angle traverse to determine highly-constrained solutions to the rotating vector model which show conclusively that PSR B0906-49 is an orthogonal rotator.
Kramer, M., Johnston, S.
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

The effect of pole length on physiological and perceptual responses during G3 roller ski skating on uphill terrain.

open access: yesPLoS ONE, 2019
The benefits of using longer than self-selected poles have been shown in double poling, but these potential benefits have not been examined in the gear 3 ski skating sub-technique (G3), during which the poling movement is very similar to double poling ...
Per-Øyvind Torvik   +3 more
doaj   +1 more source

Skiing efficiency versus performance in double-poling ergometry

open access: yesComputer Methods in Biomechanics and Biomedical Engineering, 2013
This study is on how leg utilisation may affect skiing efficiency and performance in double-poling ergometry. Three experiments were conducted, each with a different style of the double-poling technique: traditional with small knee range-of-motion and fixed heels (TRAD); modern with large knee range-of-motion and fixed heels (MOD1) and modern with ...
Holmberg, L. Joakim   +3 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy