Results 121 to 130 of about 929,781 (297)

Analogues of some fundamental theorems of summability theory

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2000
In 1911, Steinhaus presented the following theorem: if A is a regular matrix then there exists a sequence of 0's and 1's which is not A-summable. In 1943, R. C.
Richard F. Patterson
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Generalized Fermat, Double Fermat and Newton Sequences

open access: yes, 2013
[[abstract]]In this paper, we discuss the relationship among the generalized Fermat, double Fermat, and Newton sequences. In particular, we show that every double Fermat sequence is a generalized Fermat sequence, and the set of generalized Fermat ...
Du, Bau-Sen; Huang, Sen-Shan; Li, Ming-Chia
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Sequence Phenomena and Double Access Readings Generalized

open access: yes, 2003
We claim that two apparent idiosyncracies of tense  have a counterpart in other domains. (i) Sequence of Tense rules were originally posited to account for cases in which tense features appear to remain uninterpreted.
Schlenker, Philippe
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Some generalized difference double sequence spaces defined by a sequence of Orlicz-functions

open access: yesCubo, 2012
In the present paper we introduce some generalized difference double sequence spaces defined by a sequence of Orlicz-functions. We study some topological properties and some inclusion relations between these spaces.
Kuldip Raj, Sunil K Sharma
doaj  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Some Strongly Summable Double Sequence Spaces over n-normed Spaces

open access: yes, 2012
In this paper we introduce some strongly summable double sequence spaces defined by a sequence of Orlicz functions over n-normed spaces.
Sharma Sunil K.   +3 more
core   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

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