Results 51 to 60 of about 2,282,369 (288)

Bordered Floer homology and the spectral sequence of a branched double cover I

, 2014
Given a link in the three-sphere, Z. Szab\'o and the second author constructed a spectral sequence starting at the Khovanov homology of the link and converging to the Heegaard Floer homology of its branched double-cover.
Asaeda, Baldwin, Bloom, Dylan P. Thurston, Elisenda Grigsby, Kronheimer, Lee, Manolescu, Ozsváth, Ozsváth, Peter S. Ozsváth, Robert Lipshitz, Roberts, Sarkar, Sarkar   +14 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Webbed spaces, double sequences, and the Macke convergence condition

International Journal of Mathematics and Mathematical Sciences, 1999
In [3], Gilsdorf proved, for locally convex spaces, that every sequentially webbed space satisfies the Mackey convergence condition. In the more general frame of topological vector spaces, this theorem and its inverse are studied. The techniques used are
Armando García-Martínez
doaj   +1 more source

Holomorphic Poisson Cohomology [PDF]

, 2014
A holomorphic Poisson structure induces a deformation of the complex structure as Hitchin's generalized geometry. Its associated cohomology naturally appears as the limit of a spectral sequence of a double complex.
Chen, Zhuo, Grandini, Daniele, Poon, Yat-Sun   +2 more
core  

A duality for the double fibration transform

, 2012
We establish a duality within the spectral sequence that governs the holomorphic double fibration transform. It has immediate application to the questions of injectivity and range characterization for this transform.
Eastwood, Michael G., Wolf, Joseph A.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Evidence for pairing states of composite fermions in double-layer graphene

, 2019
Pairing interaction between fermionic particles leads to composite Bosons that condense at low temperature. Such condensate gives rise to long range order and phase coherence in superconductivity, superfluidity, and other exotic states of matter in the ...
Dean, C. R., Hone, J., Li, J. I. A., Shi, Q., Taniguchi, T., Watanabe, K., Zeng, Y.   +6 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Multistage axial hydro-forging sequence of double-stepped tube with large expansion ratio

International Journal of Lightweight Materials and Manufacture, 2020
In order to manufacture the double-stepped tube with large expansion ratio, a multistage axial hydro-forging sequence was proposed by combination of hydroforming with movable dies in this paper. The new forming process is divided into four stages. In the
Lei Sun, Caiyuan Lin, Guodong Wang, Guannan Chu   +3 more
doaj   +1 more source