Results 71 to 80 of about 1,416,598 (308)

On Generalized Orlicz Sequence Spaces Defined by Double Sequences

Fasciculi Mathematici, 2015
Abstract S.D. Parashar and B. Choudhary defined in 1994 certain paranorms for some Orlicz sequence spaces. Their ideas are applied later for topologization of various generalized Orlicz sequence spaces. The author determines in 2011 some alternative F-seminorms (which are also paranorms) for such spaces. In this paper these results are extended to
openaire   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Multiplicity Results of Solutions to the Double Phase Problems of Schrödinger–Kirchhoff Type with Concave–Convex Nonlinearities

Mathematics, 2023
The present paper is devoted to establishing several existence results for infinitely many solutions to Schrödinger–Kirchhoff-type double phase problems with concave–convex nonlinearities.
Yun-Ho Kim, Taek-Jun Jeong
doaj   +1 more source

Topology Changing Transitions in Bubbling Geometries

, 2005
Topological transitions in bubbling half-BPS Type IIB geometries with SO(4) x SO(4) symmetry can be decomposed into a sequence of n elementary transitions.
Horava, Petr, Shepard, Peter G.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

On Asymptotically Double Lacunary Statistical Equivalent Sequences in Probabilistic Normed Space

Analele Stiintifice ale Universitatii Ovidius Constanta: Seria Matematica, 2012
In this paper we study the concept of asymptotically double lacunary statistical convergent sequences in probabilistic normed spaces and prove some basic properties.
Esi Ayhan
doaj   +1 more source

On Ideal Convergent Difference Double Sequence Spaces in Intuitionistic Fuzzy Normed Linear Spaces

Universal Journal of Mathematics and Applications, 2021
In this paper, we introduce difference double sequence spaces ${I_{2} }^{(\mu,\upsilon)}(M,\Delta)$ and ${I_{2}^{0}}^{(\mu,\upsilon)}(M,\Delta)$ in the intuitionistic fuzzy normed linear spaces.
Esra Kamber, Selma Altundağ
doaj   +1 more source

The Blue Stragglers of the Old Open Cluster NGC 188

, 2014
The old (7 Gyr) open cluster NGC 188 has yielded a wealth of astrophysical insight into its rich blue straggler population. Specifically, the NGC 188 blue stragglers are characterized by: A binary frequency of 80% for orbital periods less than $10^4 ...
A. A. Bonačić Marinović, A. A. Tokovinin, A. M. Geller, A. M. Geller, A. M. Geller, A. M. Geller, A. M. Geller, A. R. Sandage, A. Sarajedini, A. Sills, A. Sills, B. Paczyński, B. Paxton, B. W. Carney, B. W. Carney, C. A. Nelson, C.-P. Lajoie, D. Raghavan, D. W. Latham, E. Glebbeek, E. L. Sandquist, G. Mathys, H. B. Perets, H. B. Perets, H. L. Johnson, I. Platais, J. Ahumada, J. Ahumada, J. G. Hills, J. R. Hurley, J. R. Hurley, J. R. Hurley, J.-C. Passy, J.F. Sepinsky, K. Belczynski, M. Berg van den, M. S. Hjellming, M. W. McCrea, N. Leigh, N. M. Gosnell, N. Soker, P. Bergeron, P. Gondoin, P. J. T. Leonard, P. Kroupa, P. Marigo, P. P. Eggleton, R. A. Mardling, R. D. Mathieu, R. D. Mathieu, R. Kippenhahn, R.F. Webbink, S. J. Aarseth, S. Meibom, T. E. Woods, T. Mazeh, V. P. Goranskij, W. Landsman, X. Chen, X. Chen   +59 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source