Results 71 to 80 of about 1,082,329 (323)

Adaptation in protein fitness landscapes is facilitated by indirect paths

eLife, 2016
The structure of fitness landscapes is critical for understanding adaptive protein evolution. Previous empirical studies on fitness landscapes were confined to either the neighborhood around the wild type sequence, involving mostly single and double ...
Nicholas C Wu, Lei Dai, C Anders Olson, James O Lloyd-Smith, Ren Sun   +4 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Classes of I-Convergent Double Sequences over n-Normed Spaces

Journal of Function Spaces, 2016
I introduce some new classes of I-convergent double sequences defined by a sequence of moduli over n-normed space. Study of their algebraic and topological properties and some inclusion relations has also been done.
Nazneen Khan
doaj   +1 more source

p-Bounded variation fuzzy real-valued double sequence space - doi: 10.4025/actascitechnol.v35i2.15613

Acta Scientiarum: Technology, 2013
In this paper we have introduced the notion of fuzzy real-valued p-bounded variation double sequence space 2bvp/F(1 ≤ p < ∞). We have studied some important properties like completeness, convergence free, solid, symmetric.
Amar Jyoti Dutta
doaj   +1 more source

Research on Fault-Tolerant Operation Strategy of Permanent Magnet Synchronous Motor with Common DC Bus Open Winding Phase-Breaking Fault

Energies, 2022
In some key areas, fault-tolerant control is usually needed in order to enable the motor to operate continuously in fault mode. Given that it is difficult to detect the zero-sequence current of the open winding permanent magnet synchronous motor after ...
Kangfei Lv, Xinwei Dong, Cong Zhu
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

The population of single and binary white dwarfs of the Galactic bulge

, 2018
Recent Hubble Space Telescope observations have unveiled the white dwarf cooling sequence of the Galactic bulge. Although the degenerate sequence can be well fitted employing the most up-to-date theoretical cooling sequences, observations show a ...
Calamida, A., Cojocaru, R., García-Berro, E., Torres, S.   +3 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Visual mislocalization during double-step saccades

Frontiers in Systems Neuroscience, 2015
Visual objects presented briefly at the time of saccade onset appear compressed toward the saccade target. Compression strength depends on the presentation of a visual saccade target signal and is strongly reduced during the second saccade of a double ...
Eckart eZimmermann
doaj   +1 more source

The Blue Stragglers of the Old Open Cluster NGC 188

, 2014
The old (7 Gyr) open cluster NGC 188 has yielded a wealth of astrophysical insight into its rich blue straggler population. Specifically, the NGC 188 blue stragglers are characterized by: A binary frequency of 80% for orbital periods less than $10^4 ...
A. A. Bonačić Marinović, A. A. Tokovinin, A. M. Geller, A. M. Geller, A. M. Geller, A. M. Geller, A. M. Geller, A. R. Sandage, A. Sarajedini, A. Sills, A. Sills, B. Paczyński, B. Paxton, B. W. Carney, B. W. Carney, C. A. Nelson, C.-P. Lajoie, D. Raghavan, D. W. Latham, E. Glebbeek, E. L. Sandquist, G. Mathys, H. B. Perets, H. B. Perets, H. L. Johnson, I. Platais, J. Ahumada, J. Ahumada, J. G. Hills, J. R. Hurley, J. R. Hurley, J. R. Hurley, J.-C. Passy, J.F. Sepinsky, K. Belczynski, M. Berg van den, M. S. Hjellming, M. W. McCrea, N. Leigh, N. M. Gosnell, N. Soker, P. Bergeron, P. Gondoin, P. J. T. Leonard, P. Kroupa, P. Marigo, P. P. Eggleton, R. A. Mardling, R. D. Mathieu, R. D. Mathieu, R. Kippenhahn, R.F. Webbink, S. J. Aarseth, S. Meibom, T. E. Woods, T. Mazeh, V. P. Goranskij, W. Landsman, X. Chen, X. Chen   +59 more
core   +1 more source