Results 91 to 100 of about 366,987 (281)

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Some New Double Sequence Spaces Defined by Orlicz Function in -Normed Space

open access: yesJournal of Inequalities and Applications, 2011
The aim of this paper is to introduce and study some new double sequence spaces with respect to an Orlicz function, and also some properties of the resulting sequence spaces were examined.
Savaş Ekrem
doaj  

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

On the Double Sequence Space Hϑ as an Extension of Hahn Space h

open access: yesInternational Journal of Mathematics and Mathematical Sciences
Double sequence spaces have become a significant area of research within functional analysis due to their applications in various branches of mathematics and mathematical physics.
Orhan Tuǧ   +3 more
doaj   +1 more source

$ \nu- $Conull FDK-spaces

open access: yesAIMS Mathematics
In this paper, we introduced the concepts of (strongly) $ \nu $-conull FDK-spaces, which can be regarded as double-indexed versions of FK-spaces (sequence space with coordinate functionals), by utilizing the notion of $ \nu $-convergence for double ...
Şeyda Sezgek, İlhan Daǧadur
doaj   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Some generalized difference double sequence spaces defined by a sequence of Orlicz-functions

open access: yesCubo, 2012
In the present paper we introduce some generalized difference double sequence spaces defined by a sequence of Orlicz-functions. We study some topological properties and some inclusion relations between these spaces.
Kuldip Raj, Sunil K Sharma
doaj  

ν-wedge FDK-spaces [PDF]

open access: yesMathematica Moravica
The (weak) wedgeness for FK-spaces was first defined by Bennett in 1974. Then, some results of Bennett (1974) were improved by İnce (2002) and Daˇgadur (2004) for all (weak) wedge FK spaces.
Sezgek Şeyda, Dağadur İlhan
doaj   +1 more source

Double Sequences and Iterated Limits in Regular Space

open access: yesFormalized Mathematics, 2016
Abstract First, we define in Mizar [5], the Cartesian product of two filters bases and the Cartesian product of two filters. After comparing the product of two Fréchet filters on ℕ (F1) with the Fréchet filter on ℕ × ℕ (F2), we compare limF₁ and limF₂ for all double sequences in a non empty topological space.
openaire   +3 more sources

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

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