Results 141 to 150 of about 2,897,808 (292)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
CONTINUITY OF SUPERPOSITION OPERATORS ON DOUBLE SEQUENCES SPACES OF MADDOX C_{r0} (p)
Sagır and Gungor defined the superposition operator P_g where g:N^2 × R → R by P_g ((x_{ks})) = g (k, s, x_{ks}) for all real double sequences (x_{ks}). Chew &Lee and Petranuarat & Kemprasit characterized P_g : c_0 → l_1 and _Pg : c_0 → l_q where 1 ≤ q
BIRSEN SAGIR, NIHAN GUNGOR
doaj
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
On paranormed type fuzzy I -convergent double multiplier sequences
In this article, we introduce the classes of fuzzy real valued double sequences and , where is a multiplier sequence of non-zero real numbers and is a double sequence of bounded strictly positive numbers.
M. SEN, S. ROY
doaj
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Golay complementary codes, double pulse repetition frequency transmission
This study concerns the development and investigation of a new composing method of short coded sequences and their transmission based on well-known Golay complementary codes and applied compression technique allowing to increase the signal-to-noise ratio
Igor Trots +4 more
doaj
Creative sequences and double sequences.
openaire +2 more sources
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source

