Results 131 to 140 of about 1,889,311 (309)

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

open access: yesFEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima   +7 more
wiley   +1 more source

Item 49, Drawing #14005, "E-29", Double U Company Farm Gate, 1914 [PDF]

open access: yes, 1914
The Double U Company was a land colonization business chartered in 1907 by breakfast food magnate Charles William Post (1854-1914) of Battle Creek, Michigan.

core  

Not the Definitive Version: an Interview with Ross Noble

open access: yes, 2010
In this interview, the celebrated improvisational stand-up comedian Ross Noble discusses his early influences, starting his career in the anarchic Newcastle comedy scene of the early 1990s, the gruelling experience of building his career in London, the ...
Double, Oliver, Oliver Double
core   +1 more source

Double-edge scan wavefront metrology and its application in crystal diffraction wavefront measurements

open access: yesJournal of Synchrotron Radiation
Achieving diffraction-limited performance in fourth-generation synchrotron radiation sources demands monochromator crystals that can preserve the wavefront across an unprecedented extensive range.
Fang Liu   +14 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

DSSZ-SM: A Simplified Chirp Coding Scheme with Inherent Clock Synchronization [PDF]

open access: yesRadioengineering
This study proposes a novel double-slope chirp symbol, termed double–slope start zero stop minimum (DSSZ–SM), for efficient data communication. Unlike conventional chirp coding, which often involves complex generation and synchronization, the DSSZ–SM ...
L. Kirasamuthranon   +2 more
doaj  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Master's Recital: David Malone, double bass

open access: yes, 2008
This recial is given in partial fulfillment of the requirements for the Master of Music degreeMr. Malone is a student of Paul Ellison.Sonata in D Major, BWV 1028, Johann Sebastian Bach (1685-1750) -- Concertino for flute, viola, and double bass (1925 ...

core  

Numerical model and flume experiments of single- and two-layered hillslope flow related to slope failure

open access: yes, 2010
A hillslope flow model is developed considering 3D saturated and unsaturated flow of water during rainfall events. A finite difference-based numerical model of hillslope flow processes is developed.
Nakagawa, Hajime   +5 more
core   +1 more source

Investigation of the failure mechanism and reinforcement control effect of cut slopes under climate change

open access: yesFrontiers in Earth Science
Under climate change, the increasing frequency of extreme rainfall events has made soil cut slopes more prone to progressive instability. Understanding their deformation–failure mechanisms and reinforcement effects is therefore of engineering ...
Fanping Meng
doaj   +1 more source

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