Results 191 to 200 of about 146,014 (239)

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Accelerating SCF Orbital Optimization with S-GEK/RVO: Efficient Subspace Compression and Robust Convergence. [PDF]

J Chem Theory Comput
Fdez Galván I, Weßling D, Lindh R.
europepmc   +1 more source

Scalable, Microwave‐Enabled Synthesis of Ternary WxTi1‐xO2 and Heterostructured TiO2‐WO3‐x Colloidal Nanocrystals: Carrier Dynamics and Photocatalytic Properties

Advanced Science, EarlyView.
Two microwave‐assisted synthetic methods, specifically a one‐pot and a seeded‐growth approach, are developed within a hydroalcoholic solution for the growth of single‐phase ternary WxTi1‐xO2 and heterostructured TiO2‐WO3‐x colloidal nanocrystals. Both types of nanocrystals show significant photocatalytic activity for 4‐methoxybenzyl alcohol oxidation ...
Riccardo Scarfiello, Michele Guizzardi, Angela Fiore, Armando Genco, Concetta Nobile, Elisabetta Perrone, Sara Fernanda Orsini, Clémentine Fellah, Lucian Roiban, Marianna Bellardita, Anna Maria Venezia, Giulio Cerullo, Leonardo Palmisano, Luigi Carbone   +13 more
wiley   +1 more source

Excited-State Energy Decomposition Analysis. [PDF]

Annu Rep Comput Chem
Gao J, Liu C, Chen K.
europepmc   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Detection Limits of Blood Metabolites at Physiological Concentrations Using Benchtop $$ {}^1 $$ H NMR. [PDF]

NMR Biomed
Hill AD, Travish G, Phelan M, Hayward M, Welsch CP.   +4 more
europepmc   +1 more source

Hot Electron‐Assisted Noble‐Metal‐Free Synergistic Photothermal Catalyst for Solar‐Driven Wastewater Remediation and Microbial Disinfection

Advanced Science, EarlyView.
A multifunctional Bi2Te3@CdS hybrid system is presented for solar‐driven wastewater remediation and indoor disinfection. The catalyst coated on PU foam efficiently harvests visible‐NIR light to generate heat and reactive oxygen species, enabling the rapid mineralization of organic pollutants.
Manish Kumar Sharma, Bishal Kumar Nahak, Parag Parashar, Uday Kumar Singh, Arshad Khan, Jaba Roy Chowdhury, Parthasarathi Pal, Dongwhi Choi, Hae Gyun Lim, Yu‐Lun Chueh, Zong‐Hong Lin   +10 more
wiley   +1 more source

Band-Pass Raman Spectroscopy Unlocks Compact Point-of-Care Noninvasive Continuous Glucose Monitoring. [PDF]

Anal Chem
Bresci A, Kim Y, Jue M, So PTC, Kang JW.
europepmc   +1 more source

Targeting the CMKLR1‐Mediated Signaling Rebalances Immunometabolism State in Middle‐Age Testicular Macrophages

Advanced Science, EarlyView.
In middle age, testicular CMKLR1⁺ macrophages exhibited a pro‐inflammatory immunometabolic profile, mediated by adipose signals associated with high BMI. However, inhibition of CMKLR1 signaling, either through Cmklr1 genetic ablation or treatment with a CMKLR1 antagonist peptide, can reverse this phenotype.
Zhendong Zhu, Feifei Du, Yang Liu, Jinchunzi Yang, Lei Ge, Tianxia Xiao, Mengxia Li, Jie Chen, Jia Tang, Yali Yang, Jian V. Zhang   +10 more
wiley   +1 more source

A multicenter randomized open-label phase 2 study investigating optimal antiemetic therapy for patients with advanced/recurrent gastric cancer treated with trastuzumab deruxtecan: the EN-hance study. [PDF]

Int J Clin Oncol
Aoyama T, Ooki A, Oba K, Nishikawa K, Kawabata R, Honda M, Maeda H, Kanda M, Sugiyama K, Makiyama A, Segami K, Takahashi M, Shindo Y, Namikawa T, Oshima T, Katayama A, Shiosakai K, Sakamoto J.   +17 more
europepmc   +1 more source