Prevalence of Mental Disorders in Parents With Intellectual Disabilities: A Systematic Review
ABSTRACT Background Research indicates that an increasing number of adults with intellectual disabilities (IDs) are becoming parents. Parents with ID face multiple challenges that increase their mental health risks. In order to ensure better detection and tailored care for parents with ID, this systematic review aimed to summarise the prevalence of ...
Sonya Rudra +5 more
wiley +1 more source
Changes in External Developmental Assets Across Adolescence in Low‐Income Urban Youth
ABSTRACT This study investigated longitudinal changes in external developmental assets (EDA)—support, empowerment, boundaries & expectations across ecological and interpersonal contexts of family, peers, school, and neighborhood—among predominantly Black, low‐income urban adolescents. A birth cohort of 367 adolescents (47% male) was assessed at ages 12,
Meeyoung O. Min +3 more
wiley +1 more source
Hematological Indices Abnormalities Among Sudanese Children With Down Syndrome
ABSTRACT Background and Aims Down syndrome (DS) is a genetic condition caused by the triplication of chromosome 21. Currently, there is no available published data on hematological parameters among Sudanese children with Down syndrome. Therefore, this study aimed to investigate these parameters among this population.
Manasik Elghali +5 more
wiley +1 more source
The implementation and impact of non-invasive prenatal testing (NIPT) for Down's syndrome into antenatal screening programmes: A systematic review and meta-analysis. [PDF]
Sebire E +5 more
europepmc +1 more source
A scoping review of disability representation in engineering design education
Abstract Background Design engineering coursework often includes projects that address marginalized communities, such as the disability community, and the design experience and associated curricula can impact engineering students' perspectives on user‐engaged design practices.
Mia E. Hoffman +2 more
wiley +1 more source
Identifying High‐Risk Children Safe for Same‐Day Discharge After Tonsillectomy
ABSTRACT Objective Current guidelines recommend overnight admission for children with severe obstructive sleep apnea (OSA) and obesity undergoing tonsillectomy, although most have uneventful postoperative courses. We aimed to identify low‐risk subgroups within this high‐risk population who may be candidates for same‐day discharge. Methods Retrospective
Amy Ho +9 more
wiley +1 more source
Utility of Preoperative Cardiac Workup for Children With Very Severe Obstructive Sleep Apnea
In this retrospective study, we aimed to examine the prevalence and utility of obtaining a preoperative cardiac workup in children with very severe obstructive sleep apnea (OSA) prior to adenotonsillectomy. Of 144 patients with very severe OSA, 38 patients (26.4%) underwent a preoperative cardiac workup, and three of those 38 had abnormal findings ...
Danny A. Elias +3 more
wiley +1 more source
Organoids: Current Applications and Future Directions
Organoids are three‐dimensional multicellular structures derived from stem cells or primary tissues that recapitulate key structural and functional features of native organs. Advances in stem cell biology, biomaterials, and bioengineering have established organoids as powerful platforms for studying human development and disease mechanisms, drug ...
Yueqi Leng +14 more
wiley +1 more source
Clinical Epigenomics in Rare Diseases: Interpreting DNA Methylation Episignatures
Clinical epigenomics extends rare‐disease diagnostics beyond DNA sequence by revealing the downstream regulatory consequences of genetic variation. DNA methylation episignatures provide functional evidence that can support diagnosis, refine variant interpretation, distinguish overlapping disorders, and complement genomic, and multi‐omic testing ...
Himanshu Goel, Shuxiang Goh, Luke Stuart
wiley +1 more source
Abstract There is growing interest in children's reading experiences, both volitional and those initiated by, or connected to, school‐related reading. However, the majority of this research focuses on the reading experiences of neurotypical children; limiting understanding and the potential to improve support for other groups of children.
Katie Cebula, Sarah McGeown
wiley +1 more source

