Results 191 to 200 of about 5,393,020 (341)

Down-regulation of gut-enriched Krüppel-like factor expression in esophageal cancer

, 2002
Nan Wang
openalex   +2 more sources

Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex [PDF]

, 2014
Hong Geun Park, Hyun Sook Yu, Soyoung Park, Yong Min Ahn, Yong Sik Kim, Se Hyun Kim   +5 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

TRIM21 promotes K63-linked ubiquitination of ALKBH5 and suppresses cuproptosis via down-regulation of LIAS in esophageal squamous cell carcinoma. [PDF]

Commun Biol
Feng A, He L, Li Z, Wang Z, Sun M, Zhao Z, Zhang Z, Fang K, Wu H, Wang X, Zhang S, Chen Z, Zhang L, Chen T, Xu M.   +14 more
europepmc   +1 more source

Antiproliferative and Proapoptotic Activity of Sunitinib on Endothelial and Anaplastic Thyroid Cancer Cells via Inhibition of Akt and ERK1/2 Phosphorylation and by Down-Regulation of Cyclin-D1 [PDF]

, 2013
Teresa Di Desidero, Anna Fioravanti, Paola Orlandi, Bastianina Canu, Riccardo Giannini, Nicla Borrelli, Shan Man, Ping Xu, Gabriella Fontanini, Fulvio Basolo, Robert S. Kerbel, Giulio Francia, Romano Danesi, Guido Bocci   +13 more
openalex   +1 more source

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Down-regulation of gastrin-releasing peptide in medial orbitofrontal cortex to nucleus accumbens projections contributes to allodynia and negative affect. [PDF]

Sci Adv
Zhao T, Chen A, Dai D, Li Z, Feng E, Gao XF, Xiong L.   +6 more
europepmc   +1 more source

DLC1 suppresses distant dissemination of human hepatocellular carcinoma cells in nude mice through reduction of RhoA GTPase activity, actin cytoskeletal disruption and down-regulation of genes involved in metastasis

, 2008
Xiaoling Zhou, Drazen B. Zimonjic, Sang‐Won Park, Xu-Yu Yang, Marian E. Durkin, Nicholas C. Popescu   +5 more
openalex   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Reciprocal interaction between cortical SST and PV interneurons in top-down regulation of retinothalamic refinement. [PDF]

Proc Natl Acad Sci U S A
Jiang Q, Wu SJ, Fishell G, Chen C.
europepmc   +1 more source