Results 201 to 210 of about 5,393,020 (341)

Down-regulation of MARCKS-related Protein (MRP) in Macrophages Infected with Leishmania [PDF]

, 1999
Sally Betz Corradin, Jacques Mauël, Adriana Ransijn, Christoph Stürzinger, Guy Vergères   +4 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Down-regulation of HSPA9 reduces tyrosine hydroxylase-positive neurons in mouse substantia nigra and induces Parkinson's disease-like motor impairments. [PDF]

Anim Cells Syst (Seoul)
Hyung H, Jang S, Kim SY, Bae JE, Park JY, Lim SG, Ko J, Jang S, Kim JB, Chae HY, Park S, Yi J, Choi DK, Kim MO, Lee HS, Cho DH, Young Ryoo Z.   +16 more
europepmc   +1 more source

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-BclxL strategies through Mcl-1 down-regulation [PDF]

, 2018
Marie-Laure Bonnefond, Romane Florent, Sophie Lenoir, Bernard Lambert, Edwige Abeilard, Florence Giffard, Marie-Hélène Louis, Nicolas Elie, Mélanie Briand, Denis Vivien, Laurent Poulain, Pascal Gauduchon, Monique N’Diaye   +12 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Constitutive down-regulation of liguleless alleles in sorghum drives increased productivity and water use efficiency. [PDF]

Plant Biotechnol J
Jaikumar N, Quach T, Ge Z, Nersesian N, Sato SJ, McCoy SM, Guo M, Leakey ADB, Long SP, Clemente TE.   +9 more
europepmc   +1 more source

UPREGULATION OF ENDOTHELIN (ETA AND ETB) RECEPTORS AND DOWN REGULATION OF NITRIC OXIDE SYNTHASE IN THE DETRUSOR OF A RABBIT MODEL OF BLADDER OUTLET OBSTRUCTION

, 1999
Cecil S. Thompson, Masood Khan, Mick Dashwood, Faiz Mumtaz, Dimitri P. Mikhailidis, Robert Morgan   +5 more
openalex   +1 more source

Changing Ecosystem Dynamics in the Laurentian Great Lakes: Bottom-Up and Top-Down Regulation

, 2014
D. Bunnell, R. Barbiero, S. Ludsin, C. P. Madenjian, G. Warren, D. Dolan, Travis O. Brenden, R. Briland, O. T. Gorman, Ji X. He, T. Johengen, B. Lantry, B. Lesht, T. Nalepa, S. C. Riley, C. Riseng, Ted Treska, I. Tsehaye, M. Walsh, D. Warner, B. Weidel   +20 more
semanticscholar   +1 more source

Beta 1- and beta 2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: coupling of both receptor subtypes to muscle contraction and selective beta 1-receptor down-regulation in heart failure.

Circulation Research, 1986
M. Bristow, R. Ginsburg, V. Umans, M. Fowler, W. Minobe, R. Rasmussen, P. Zera, R. Menlove, P. Shah, S. Jamieson   +9 more
semanticscholar   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source