Results 161 to 170 of about 10,165,257 (315)
Correction: Knowledge, attitudes, and practices of organ, tissue, and cell donation in Nicaragua. [PDF]
PLOS One Staff.
europepmc +1 more source
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun+10 more
wiley +1 more source
Enabling pan-repository reanalysis for big data science of public metabolomics data. [PDF]
El Abiead Y+21 more
europepmc +1 more source
COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo+15 more
wiley +1 more source
Correction: An explainable ensemble approach for advanced brain tumor classification applying Dual-GAN mechanism and feature extraction techniques over highly imbalanced data. [PDF]
PLOS One Staff.
europepmc +1 more source
Unveiling Multi‐Scale Architectural Features in Single‐Cell Hi‐C Data Using scCAFE
scCAFE is a deep learning framework designed to identify multi‐scale 3D genome architectural features from single‐cell Hi‐C data without dense imputation. It predicts chromatin loops, TAD‐like domains, and A/B compartments, enabling efficient characterization of organization at the single‐cell level. scCAFE also identifies marker loop anchors, offering
Fuzhou Wang+12 more
wiley +1 more source
Protocol for genetic analysis of population-scale ultra-low-depth sequencing data. [PDF]
Zeng J+8 more
europepmc +1 more source