Results 31 to 40 of about 1,189,976 (248)

Rossolimo–Melkersson–Rosenthal syndrome in 14 years old child with Down`s syndrome. Case report

open access: yesКлинический разбор в общей медицине, 2023
Rossolimo–Melkerson–Rosenthal syndrome is not so often diagnosed in childhood. It is noted that children's syndrome occurs as a monosymptom in the form of macrocheilitis.
Larisa I. Glebova   +1 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Downs, Wilbur G. -- 1987 -- Correspondence, Individual -- letter, 1987-11-13

open access: yes, 1987
Letter from Downs, Wilbur G. to Sabin, Albert B.
Downs, Wilbur G., 1913-1991
core   +1 more source

Is Memantine a Potential Therapeutic for Rett Syndrome?

open access: yesFrontiers in Neuroscience, 2013
Memantine is a low-affinity voltage-dependent non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist. It is classified as a neuroprotective aminoadamantane.
Olivia eBello   +3 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

open access: yesAging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi   +3 more
wiley   +1 more source

High‐Resolution MRI Revealed Different Etiology‐Specific Associations With Cerebral Infarction in Adult Moyamoya Vasculopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐resolution MRI enables detailed assessment of intracranial vessel wall pathology in moyamoya vasculopathy. We aimed to classify adult moyamoya vasculopathy etiologies using high‐resolution MRI and to examine subtype‐specific associations between high‐resolution MRI features and ischemic infarction.
Guangsong Han   +8 more
wiley   +1 more source

Down Syndrome and Parity

open access: yesPublic Health Genomics, 1999
<i>Objective:</i> To investigate the effect of parity on Down syndrome (DS). <i>Methods:</i> The study was conducted on data from Northeast Italy (NEI) (1981–1996) and Sicily (ISMAC) (1991–1996) Congenital Malformation Registries.
CLEMENTI, MAURIZIO   +4 more
openaire   +3 more sources

Dentofacial changes and oral health status in mentally challenged children

open access: yesJournal of Indian Society of Pedodontics and Preventive Dentistry, 2005
The study was carried out on 69 mentally challenged individuals. They were subjected to detailed clinical evaluation for dentofacial abnormalities and oral health status.
Bhowate Rahul, Dubey A
doaj  

Multi-Modal Imaging in Down's Syndrome: Maximizing Utility Through Innovative Neuroimaging Approaches

open access: yesFrontiers in Neurology, 2021
In recent decades, the field of neuroimaging has experienced a surge of popularity and innovation which has led to significant advancements in the understanding of neurological disease, if not immediate clinical translation.
Stephanie S. G. Brown   +3 more
doaj   +1 more source

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