Results 121 to 130 of about 109,140 (374)

PROTAC‑Mediated HMGCR Depletion Reprograms Lipid Metabolism in Breast Cancer to Potentiate Photoimmunotherapy via Ferroptosis

Advanced Science, EarlyView.
This work introduces a study that identifies HMGCR as a novel target in TNBC and develops a light‐gated PROTAC nanomedicine. Upon irradiation, this agent selectively degrades HMGCR, reprogramming lipid metabolism to induce ferroptosis and potent antitumor immunity, thereby significantly enhancing photoimmunotherapy efficacy.
Tong Su, Guang Li, Yudong Guan, Qi Tian, Youzhi Qi, Yanqiu Zhang, Wenqian Wei, Xinxin Duan, Jiaxin Rui, Hongyan Zhu, Zengping Lin, Changchuan Xie, Zheni Xu, Yaying Wu, Xin Peng, Zhenjie Wang, Kun Chen, Xiaoyan Xin, Bing Zhang   +18 more
wiley   +1 more source

How AI Shapes the Future Landscape of Sustainable Building Design With Climate Change Challenges?

Advanced Science, EarlyView.
This review examines how artificial intelligence reshapes sustainable building design faced with climate change challenges. The authors synthesize existing studies to demonstrate AI's transformative potential across design lifecycle phases from climate‐aware form generation to performance optimization.
Pengyuan Shen, Xiaoni Gao, Shuai Lu, Yi Zhang, Xing Zheng, Matthaios Santamouris   +5 more
wiley   +1 more source

Study on the Effect of Shortwave Radiation in Land Surface Temperature Downscaling over Rugged Terrain

Remote Sensing
Land surface temperature (LST) is an important parameter in the surface system with drastic variation in spatial and temporal domains. The protection of the ecological environment in mountainous areas and the monitoring of natural disasters require the ...
Shumin Wang, Jie Cheng, Qiang Liu
doaj   +1 more source

A New Surface Waters Downscaling Approach Applicable at Global Scale

Remote Sensing
A surface water extent downscaling framework was developed in the past using a floodability index based on topography. We presented here a new downscaling approach including several improvements.
Thu-Hang Nguyen, Filipe Aires
doaj   +1 more source

Molecular Sieve Promoted Growth of Ferroelectric Trilayer 3R‐MoS2 for Polarization‐Dependent Reconfigurable Optoelectronic Synapses

Advanced Science, EarlyView.
The noncentrosymmetric trilayer rhombohedral‐stacked MoS2 nanoflakes with enhanced sliding ferroelectric properties are synthesized via a molecular sieve‐assisted chemical vapor deposition process. The switchable polarization states, combined with the exceptional light/gate voltage modulated electrical properties of these nanoflakes, enable broadband ...
Qichao Xue, Jincheng Zhang, Yuying Wang, Yu Wang, Kuiwei Li, Yuxuan Chen, Fang Zhong, Qing Li, Ning Zhou, Chenying Yang, Yuchuan Shao, Tao Liang   +11 more
wiley   +1 more source

Spatiotemporal Statistical Downscaling for the Fusion of In-lake and Remote Sensing Data [PDF]

, 2018
This paper addresses the problem of fusing data from in-lake monitoring programmes with remote sensing data, through statistical downscaling. A Bayesian hierarchical model is developed, in order to fuse the in-lake and remote sensing data using ...
Groom, Steve, Hunter, Peter, Miller, Claire, Scott, Marian, Simis, Stefan, Spyrakos, Evangelos, Tyler, Andrew, Wilkie, Craig   +7 more
core  

Approaching the Monolayer Limit of Carbon Layers by Pyrolysis of Polymer Films

Advanced Electronic Materials, EarlyView.
Wafer‐scale functional devices based on pyrolyzed photoresist films are synthesized directly on target substrates without catalysts or transfer steps, with channels reaching the monolayer limit (0.34 nm). X‐ray photoelectron spectroscopy confirms predominant sp2 character, Raman spectroscopy reveals evolving nanocrystallinity, and transmission electron
Natalie Galfe, Florian Herdl, Sebastian Klenk, Moritz Quincke, Cormac Ó Coileáin, Kangho Lee, Ute Kaiser, Georg S. Duesberg   +7 more
wiley   +1 more source

The potential impacts of climate change on the distribution of Nepenthes and dipterocarps of the Trus Madi Forest Reserve [PDF]

, 2011
Publisher ...
Burslem, David Francis Robert Philip, Khoo, Eyen, Majapun, Richard, Maycock, Colin R, Pereira, Joan, Sugau, John   +5 more
core  

Downscaling data assimilation algorithm with applications to statistical solutions of the Navier-Stokes equations

, 2018
Based on a previously introduced downscaling data assimilation algorithm, which employs a nudging term to synchronize the coarse mesh spatial scales, we construct a determining map for recovering the full trajectories from their corresponding coarse mesh
Biswas, Animikh, Foias, Ciprian, Mondaini, Cecilia F., Titi, Edriss S.   +3 more
core   +1 more source

Seamless downscaling of the ESA CCI soil moisture data at the daily scale with MODIS land products

, 2021
Wei Zhao, Fengping Wen, Qunming Wang, Nilda Sánchez, María Piles   +4 more
openalex   +2 more sources