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Downstream Processing in Marine Biotechnology
2005Downstream processing is one of the most underestimated steps in bioprocesses and this is not only the case in marine biotechnology. However, it is well known, especially in the pharmaceutical industry, that downstreaming is the most expensive and unfortunately the most ineffective part of a bioprocess.
Kai, Muffler, Roland, Ulber
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Downstream Processing in the Biotechnology Industry
Molecular Biotechnology, 2002The biotechnology industry today employs recombinant bacteria, mammalian cells, and transgenic animals for the production of high-value therapeutic proteins. This article reviews the techniques employed in this industry for the recovery of these products.
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Continuous downstream processing of biopharmaceuticals
Trends in Biotechnology, 2013Continuous manufacturing has been applied in many different industries but has been pursued reluctantly in biotechnology where the batchwise process is still the standard. A shift to continuous operation can improve productivity of a process and substantially reduce the footprint.
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Downstream processing of monoclonal antibodies.
Australian journal of biotechnology, 1989The rapid world-wide growth of the biotechnology industry has been based on the development of genetic engineering and cell fusion techniques, by which proteins having valuable diagnostic, therapeutic, industrial and other applications can be produced in commercial quantities.
Gunnersen, J. M. +6 more
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Biosafety in Downstream Processing
1990Separation processes in biotechnology such as centrifugation and homogenisation may pose a serious health risk to personnel due to their potential to produce aerosols of potentially allergenic biological material. Bioprocessing equipment should be monitored for released biological aerosols to ensure its safe operation.
Allan M. Bennett +2 more
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Downstream processing and structural confirmation of pullulan - A comprehensive review
International Journal of Biological Macromolecules, 2022Dhandeep Singh +2 more
exaly
Intensified Downstream Processing of Monoclonal Antibodies Using Membrane Technology
Biotechnology Journal, 2021Balaji Somasundaram, Linda Lua
exaly