Results 281 to 290 of about 413,339 (385)

Engineered Hydrogels Revolutionize Locoregional Cancer Immunotherapy

Advanced NanoBiomed Research, EarlyView.
This review systematically summarizes the latest research progress on injectable hydrogels in cancer immunotherapy, highlighting their unique advantages in precise immune activation, local drug‐controlled release, and immune microenvironment remodeling. These features provide innovative solutions to overcome the bottlenecks of systemic side effects and
Jiyong Wei, Chunliu Huang, Zenghua Zhou, Yanni Lan   +3 more
wiley   +1 more source

Engineering a Multifunctional Nanozyme Platform for Synergistic Melanoma Therapy: Integrating Enzyme Activity, Immune Activation, and Low‐Temperature Photothermal Effects

Angewandte Chemie, EarlyView.
This study innovatively develops a multifunctional, multienzyme‐active nanoplatform (FeCP@PDA‐GOx), aimed at overcoming the limitations of traditional cancer therapies and achieving precise, efficient, and long‐lasting melanoma treatment. By integrating starvation therapy, CDT, mPTT, and immunotherapy, FeCP@PDA‐GOx generates a multidimensional ...
Qihang Ding, Haowei Liu, Lishan Yan, Liang Chen, Yu Chen, Jong Seung Kim, Ling Mei   +6 more
wiley   +2 more sources

Mechanism of myocardial damage induced by doxorubicin <i>via</i> calumenin-regulated mitochondrial dynamics and the calcium-Cx43 pathway. [PDF]

World J Cardiol
Shi H, Yang SA, Bai LY, Du JJ, Wu Z, He ZH, Liu H, Cui JY, Zhao M.   +8 more
europepmc   +1 more source

Progress in Biomimetic Microdevices for Anticancer Drug Screening and their Potential for Enhancing In Vivo Efficacy

Advanced NanoBiomed Research, EarlyView.
Biomimetic microdevices are redefining anticancer drug screening by mimicking complex tumor microenvironments. This review highlights advances in microfluidic systems, cell microarrays, and in vivo‐like models, offering new insights into drug efficacy prediction and personalized medicine. The development of effective anticancer drugs remains a critical
Ching‐Te Kuo, Yen‐Tzu Liao, Hsinyu Lee   +2 more
wiley   +1 more source

MOF Coating Enhances the Ion Tolerance of Micromotors

Angewandte Chemie, EarlyView.
This work reported a novel method to significantly enhance the ion tolerance of EMNMs using a MOF coating via controllable heteroepitaxial growth, enabling effective motion in high‐salt environments and propulsion through biological tissues under 980 nm NIR light, with potential applications in targeted drug delivery.
Leyan Ou, Kunfeng Liu, Yifan Zhang, Wanyuan Li, Zixian Liang, Dapeng Lei, Hao Sun, Mojun Chen, Jizhuang Wang, Jinyao Tang, Dan Li   +10 more
wiley   +2 more sources

A Retrospective Study of Chemotherapy-Related Extravasation Events in Dogs and Cats. [PDF]

J Vet Intern Med
Martens E, Hritz R, Clifford C, Mullin C, Camero C, Shiu KB, Chan C, Del Alcazar C, DeRegis C, Donnelly L, Marker B, Purzycka K, Vickery K.   +12 more
europepmc   +1 more source

Nanoparticles Functionalized with Polymer Brushes for Gene Delivery

Advanced NanoBiomed Research, EarlyView.
The engineering of the next generation gene delivery vectors requires the precise control of the architecture and physicochemical interactions controlling the transport, targeting, uptake, and release of nucleic acid materials to targeted cells. Polymer brush‐functionalized nanomaterials offer unprecedented control over such design and properties, and ...
Carlos E. Neri‐Cruz, Julien E. Gautrot
wiley   +1 more source

Communicative Nanomotors Reprogram Cancer Cell Death via Pyroptosis

Angewandte Chemie, EarlyView.
Communicative nanomotors respond to elevated ROS in the tumor microenvironment, enabling active communication and selective mitochondrial targeting through non‐covalent surface engineering. Their precise interaction with cells induces mitochondrial damage, cytochrome c release, and pyroptotic cell death, while chemotactic motility ensures deeper tumor ...
Mingchen Sun, Luc van Oss, Chenxuan Wan, Daniela A. Wilson   +3 more
wiley   +2 more sources

The role of FOXA1 and miR-212-3p in molecular modulation of doxorubicin resistance in liver cancer. [PDF]

Med Oncol
Elfiky A, El-Guendy N, Badr AM, Mohammed MA, Wahab AHAA.   +4 more
europepmc   +1 more source

High yield conversion of doxorubicin to 2-pyrrolinodoxorubicin, an analog 500-1000 times more potent: structure-activity relationship of daunosamine-modified derivatives of doxorubicin.

, 1996
Attila Nagy, Patricia Armatis, Andrew V. Schally   +2 more
openalex   +1 more source