Doxorubicin-NFL-TBS.40-63 peptide Gold Complex Nanovector (DOX IN-NFL@AuNPs): Efficacy Evaluation in a mouse transplantation tumor model induced by PANC-1/ADR human pancreatic cancer resistant strain cells. [PDF]
Liu H+5 more
europepmc +1 more source
Innovative transdermal drug delivery systems: Benefits, challenges, and emerging application
The graphical abstract illustrates the diverse nanostructures employed in transdermal drug delivery systems, highlighting their unique mechanisms to penetrate the intricate layers of skin. It provides a detailed representation of the skin's complex anatomy, emphasizing the challenges posed by its barrier properties.
Syed Waqas Ali Shah+9 more
wiley +1 more source
ChemoID-guided therapy improves objective response rate in recurrent platinum-resistant ovarian cancer randomized clinical trial. [PDF]
Herzog TJ+13 more
europepmc +1 more source
Combating cancer immunotherapy resistance: a nano‐medicine perspective
Abstract Cancer immunotherapy offers renewed hope for treating this disease. However, cancer cells possess inherent mechanisms that enable them to circumvent each stage of the immune cycle, thereby evading anti‐cancer immunity and leading to resistance.
Xiangyi Kong+10 more
wiley +1 more source
Dual role of p21 in regulating apoptosis and mitotic integrity in response to doxorubicin in colon cancer cells. [PDF]
Kim H+6 more
europepmc +1 more source
Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen+46 more
wiley +1 more source
[<sup>18</sup>F]-FLT-PET to evaluate how the sequencing of chemotherapies impacts the efficacy of combination treatment in mouse models of triple-negative breast cancer. [PDF]
Lu Y+7 more
europepmc +1 more source
Abstract Background The standard adjuvant chemotherapy for early‐stage, high‐risk breast cancer includes anthracyclines and taxanes. While anthracycline‐based regimens have proven effective in human epidermal growth factor receptor 2 (HER2)‐positive breast cancer, their efficacy may be reduced in HER2‐negative patients due to the lack of co ...
Yu Song+6 more
wiley +1 more source
Feasibility of Pressurized Intraperitoneal Aerosol Chemotherapy (PIPAC) in a Rabbit Model of Peritoneal Metastases: PIPALIM Project. [PDF]
Bardet SM+9 more
europepmc +1 more source