Results 221 to 230 of about 155,628 (290)
Zic family member 5 promotes RIO kinase 3 expression to enhance pancreatic cancer survival
This study demonstrates that targeting ZIC5 increases gemcitabine sensitivity and induces pancreatic cancer shrinkage in vivo. The findings also show that ALDH3B1, PTGES, and TUFT1, the downstream genes of ZIC5, contribute to gemcitabine resistance in pancreatic cancer cells.
Reiko Satow+7 more
wiley +1 more source
The Inhibitory Effect of Metronidazole and Doxycycline-HCl on proMMP-3 Production in Gingival Fibroblast [PDF]
Hak-Joo Kim+4 more
openalex +1 more source
Regions flanking the PCNA‐binding motif in p21 contribute to high‐affinity binding through complementary charges without specific contacts. These regions affect p21 abundance, but their exact Lys/Arg composition is unimportant for PCNA binding. Conversely, both context and Lys/Arg composition of the N‐terminal flanking region are crucial for p21 ...
Signe Simonsen+8 more
wiley +1 more source
Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols. [PDF]
Kakakhel MZJ+4 more
europepmc +1 more source
Hidradenitis Suppurativa Treatment During Pregnancy and Lactation: Navigating Challenges
ABSTRACT Hidradenitis suppurativa (HS), or acne inversa, is a chronic inflammatory skin condition primarily affecting skin folds such as the axilla, groins, and the inframammary, perineal, and perianal regions. It is characterized by painful abscesses, sinus tracts, and scarring.
Laşin Özbek+3 more
wiley +1 more source
Comparison of initial empirical antibiotic regimens in severe community-acquired pneumonia: a network meta-analysis. [PDF]
Wang M+6 more
europepmc +1 more source
The Microbiome in Hidradenitis Suppurativa Tunnels: A Systematic Review
ABSTRACT Hidradenitis suppurativa (HS) is a chronic inflammatory disease that affects the pilosebaceous units, particularly in large skin folds. The pathophysiology of HS is multifactorial, with evidence suggesting that the microbiome plays a crucial role in perpetuating inflammation.
Alberto Soto‐Moreno+6 more
wiley +1 more source
Measured Versus Self-Reported Compliance With Doxycycline Therapy for Chlamydia-Associated Syndromes
Laura H. Bachmann+3 more
openalex +1 more source