Results 261 to 270 of about 150,359 (342)

ICMT supports BRAF^V600E-driven tumor growth by membrane targeting of the CAAX protein INPP5E. [PDF]

Proc Natl Acad Sci U S A
Yang X, Qiao X, Schmidt S, Eklund EA, Ebner-Walter C, Ivarsson E, Crespo MA, Kersemakers N, Dzanan JJ, Thorisson B, Lundgren C, Lim HC, Shkoukani S, Tüksammel E, Xu X, Sayin VI, Martín-Fontecha M, Ortega-Gutiérrez S, Dalin M, Bergo MO.   +19 more
europepmc   +1 more source

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

Engagement in Care and Sexually Transmitted Infection Screening Among Patients Prescribed Doxycycline Postexposure Prophylaxis at a Midwestern HIV/Preexposure Prophylaxis Clinic. [PDF]

Open Forum Infect Dis
Lo V, Nguyen K, Bernhard S, Havens JP, Bares SH, Davis JM, Scarsi KK, Sunagawa SW.   +7 more
europepmc   +1 more source

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host–Biofilm Interactions and Reduces Bone Loss in Periodontitis

Journal of Periodontal Research, EarlyView.
BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo, Dong Woo Lee, Ji‐Young Lee, Sanghui Seok, Yu‐Bin Kim, Jue‐Yeon Lee, Shin‐Young Park, Young Dan Cho, Yang Jo Seol, Yoon Shin Park, Shahram Ghanaati, Homayoun H. Zadeh, Chong Pyung Chung, Yoon Jeong Park   +13 more
wiley   +1 more source

Effects of doxycycline on intrusive experimental trauma memory: a pre-registered, randomized double-blind placebo-controlled trial. [PDF]

Transl Psychiatry
Meister L, Rosi-Andersen A, Bavato F, Xia Y, Bach DR, Kleim B.   +5 more
europepmc   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Comparative Efficacy of Topical N-Acetylcysteine-Doxycycline versus Benzoyl Peroxide-Doxycycline in Moderate Acne Vulgaris: An Add-on Double-Blind Randomized Controlled Trial. [PDF]

Dermatol Pract Concept
Parvizi MM, Mosallanezhad P, Hekmat M, Alipour S, Haghighi NF.   +4 more
europepmc   +1 more source

Multidrug resistance of bacterial pathogens in canine pyometra

Journal of Small Animal Practice, EarlyView.
Objectives To characterise multidrug antimicrobial resistance and pathogenicity profiles of bacteria isolated from different anatomical sites in bitches with pyometra, emphasising their clinical relevance for diagnosis and therapeutic decision‐making in small animal practice.
M. G. M. Camozzi, S. B. Waller, E. C. Castelhano, A. L. S. Neves, B. R. Arrais, J. F. N. Pinto, B. G. Alves, C. N. Moreira   +7 more
wiley   +1 more source

The use of tetracyclines in hidradenitis suppurativa: A focused systematic review

JAAD Reviews
Zahidul Islam, BA, Hansen Tai, BA, Sarah Romanelli, BS, Isha M. Gandhi, BS, Solbie Choi, BS, Caroline Delbourgo Patton, MA, MSLIS, Kristina L. Campton, MD   +6 more
doaj   +1 more source

Vacuolar iron export alters the synergy between doxycycline and fluconazole by affecting cidal ROS levels in <i>Candida albicans</i>. [PDF]

mBio
Van Genechten W, Holtappels M, De Jonge M, Vergauwen R, Cornips G, Van Dijck P.   +5 more
europepmc   +1 more source