Results 121 to 130 of about 85,599,608 (253)
Alogliptin: a new addition to the class of DPP-4 inhibitors
, 2009 Radha Andukuri, Andjela Drincic, Marc RendellDivision of Endocrinology, Department of Medicine, Creighton University School of Medicine, Omaha, Nebraska, USABackground: Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the ...
Radha Andukuri +2 more
core
Phytotherapy Research, EarlyView.Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source
Phytotherapy Research, EarlyView.Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca +5 more
wiley +1 more source
A Scalable Synthesis of an Azabicyclooctanyl Derivative, a Novel DPP-4 Inhibitor
, 2016 A practical synthetic strategy to a chiral azabicycclooctanyl derivative (1), a potent DPP-4 inhibitor, starting from a commercially available nortropine is described.
Chuanqin Liu (2407684) +11 more
core +1 more source
Anti‐obesity medications and incident ocular outcomes: A systematic review and network meta‐analysis
VIEW, EarlyView.In this systematic review and network meta‑analysis of 140 studies, anti‑obesity medications showed heterogeneous ocular safety profiles. Semaglutide was associated with higher NAION risk (observational data), whereas dual/multi‑agonists and glucagon‐like peptide‐1 receptor agonists demonstrated favourable glaucoma and overall ocular outcomes ...
Linge Jian +5 more
wiley +1 more source
Surface Energy Modification of Semi-Random P3HTT-DPP
, 2016 Alkyl solubilizing side chains on conjugated polymers can serve as a handle for modifying polymer properties. Recently, oligo-ether and semifluoro alkyl side chains were utilized to tune the surface energy of random P3HT-based polymers without changing ...
Sangtaik Noh (1565080) +3 more
core +1 more source
BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.ABSTRACT Objective An increasing number of women of childbearing age worldwide are using glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and are advised to use effective contraception during treatment. Nevertheless, maternity services are encountering increasing numbers of women exposed to GLP‐1 RAs shortly before conception or during pregnancy ...
Katherine G. Y. Lau +6 more
wiley +1 more source
Risk of hyperkalaemia in patients with type 2 diabetes mellitus prescribed with SGLT2 versus DPP-4 inhibitors [PDF]
To investigate the risk of hyperkalaemia in new users of sodium–glucose cotransporter 2 (SGLT2) inhibitors vs. dipeptidyl peptidase-4 (DPP-4) inhibitors among patients with type 2 diabetes mellitus (T2DM).
Tsang, Christopher Tze Wei +13 more
core +1 more source
Andrology, EarlyView.ABSTRACT Background Drugs used for diabetes and obesity increasingly shape male sexual and reproductive counseling, but clinical studies, trial registrations, regulatory labels, and patents answer different questions. Objectives The objective is to map these sources and define what each can support when counseling men receiving metabolic drugs ...
Marek Broul +3 more
wiley +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
Andrology, EarlyView.ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source