Results 161 to 170 of about 85,599,608 (253)

Cardiovascular Outcomes of Insulin Degludec Versus Insulin Glargine in Trial‐Eligible and Ineligible Populations: A DEVOTE‐Inspired Target Trial Emulation Using the Swedish National Diabetes Register

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare cardiovascular outcomes associated with the initiation of insulin degludec versus insulin glargine using a target trial emulation approach in nationwide real‐world data. Materials and Methods We conducted a nationwide observational cohort study using Swedish health registers, including the National Diabetes Register ...
Thomas Nyström   +16 more
wiley   +1 more source

Linagliptin, a Selective DPP-4 Inhibitor, Attenuates Ketamine- and Diazepam-Induced Deficits in Passive Avoidance Performance in Mice. [PDF]

open access: yesBrain Sci
Fronc K   +11 more
europepmc   +1 more source

Changes in Muscle Strength Following Semaglutide Treatment in Adults: A Systematic Review With Meta‐Analysis of Handgrip Strength

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To systematically review and quantitatively synthesize within‐group changes in skeletal muscle strength following semaglutide treatment in adults. Materials and Methods This PRISMA 2020 systematic review was registered in PROSPERO (CRD420251185935).
Luís Guilherme Machado   +9 more
wiley   +1 more source

Endogenous GIP signaling is indispensable for DPP-4 inhibitor-mediated metabolic control in mice. [PDF]

open access: yesJ Diabetes Investig
Kubota-Okamoto S   +17 more
europepmc   +1 more source

DPP-4 Inhibitor and Sulfonylurea Differentially Reverse Type 2 Diabetes-Induced Blood-Brain Barrier Leakage and Normalize Capillary Pericyte Coverage. [PDF]

open access: yesDiabetes, 2023
Elabi OF   +8 more
europepmc   +1 more source

Neuropsychiatric Outcomes Associated With GLP‐1 Receptor Agonist Use in Medicare Beneficiaries With Type 2 Diabetes: Variation by Treatment Pattern and Obesity Status

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptors are expressed in brain regions governing mood, reward and stress, yet the neuropsychiatric effects of GLP‐1 receptor agonist (GLP‐1 RA) therapy remain poorly characterized. We estimated associations between GLP‐1 RA use and neuropsychiatric disorders and variation by obesity status and treatment ...
Seo Hyon Baik   +4 more
wiley   +1 more source

Does DPP-4 inhibitor treatment affect the clinical outcomes of COVID-19 in type 2 diabetes mellitus patients? [PDF]

open access: yesNorth Clin Istanb, 2022
Erol RS   +9 more
europepmc   +1 more source

Association of GLP‐1 Receptor Agonists With Gastrointestinal and Liver Outcomes in Adults With Type 2 Diabetes: A Target Trial Emulation Study

open access: yes
Diabetes, Obesity and Metabolism, EarlyView.
Dazheng Zhang   +7 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

open access: yesThe FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs   +9 more
wiley   +1 more source

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