Results 51 to 60 of about 101,617 (297)
Drugs for diabetes: part 5 DPP-4 inhibitors [PDF]
The dipeptidyl peptidase-4 (DPP-4) inhibitors are a new class of oral drugs for the treatment of type 2 diabetes. They inhibit the breakdown of glucagon-like peptide-1 (GLP-1) and increase the incretin effect in patients with type 2 diabetes. In clinical
Fisher, Miles +2 more
core
Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li +22 more
wiley +1 more source
Alogliptin: a new addition to the class of DPP-4 inhibitors [PDF]
Radha Andukuri, Andjela Drincic, Marc RendellDivision of Endocrinology, Department of Medicine, Creighton University School of Medicine, Omaha, Nebraska, USABackground: Alogliptin is an oral antihyperglycemic agent that is a selective inhibitor of the ...
Radha Andukuri +2 more
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Design, Synthesis, and in Vitro Evaluation of Novel Aminomethyl-pyridines as DPP-4 Inhibitors [PDF]
A collection of novel aminomethyl-pyridines was designed, synthesized, and investigated as potential inhibitors of DPP-4. Optimization of the screening hit afforded a number of 5-aminomethyl-pyridines with inhibitory activity in the nanomolar range ...
Karl-Heinz Wiesmüller (2160085) +2 more
core +1 more source
Synthesis of Novel Stable ZnSe Magic‐Sized Clusters and Their Direct Transformation to Quantum Dots
We have developed a low‐temperature synthetic approach that enables the fabrication of novel ZnSe MSCs with remarkable thermal stability. These stabilized MSCs serve as efficient precursors that can be readily converted to ZnSe QDs under mild conditions through simple introduction of a selenium source.
Bin Song +3 more
wiley +1 more source
Numerous studies indicate that diets with a variety of fruits and vegetables decrease the incidence of severe diseases, like diabetes, obesity, and cancer.
Poonam Kalhotra +3 more
doaj +1 more source
Background: Recent studies suggested that the increased risk of heart failure by DPP-4 inhibitors may have an interconnection with patients' baseline eGFR.
Maneesha Khalse, B Ganapathy
doaj +1 more source
DPP-4 Inhibitors: The Seinfeld of Oral Antihyperglycemics
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Arden R, Barry, Ricky D, Turgeon
openaire +3 more sources
Combination therapy with DPP-4 inhibitors and pioglitazone in type 2 diabetes: theoretical consideration and therapeutic potential [PDF]
Nasser MikhailEndocrinology Division, Olive View-UCLA Medical Center, David-Geffen School of Medicine, CA, USAAbstract: Sitagliptin and vildagliptin represent a new class of anti-diabetic agents that enhance the action of incretin hormones through ...
Nasser Mikhail
core
Self‐Accelerating Bimetallic Peroxide Nanozymes for Cascade‐Amplified Pyroptosis‐Immunotherapy
Acidic tumor microenvironment‐responsive CuZnONPs enable triple‐combination therapy via self‐supplying H2O2, cascade nanozyme activities for ROS burst, and Zn2+‐activated pyroptosis, synergizing catalytic therapy with immunotherapy to convert cold tumors into hot ones.
Xuanyi Lu +9 more
wiley +1 more source

